What do systematic reviews say?

CPAP with expiratory pressure relief vs fixed CPAP

The review found no eligible studies for this question.

• Pressure modification or humidification for improving usage of continuous positive airway pressure machines in adults… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Mepolizumab intravenous (IV) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 690 participants
  High

Reslizumab intravenous (IV) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1652 participants
  High

Reslizumab subcutaneous (SC) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 46 participants
  High

Benralizumab subcutaneous (SC) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 2786 participants
  High

Mepolizumab subcutaneous (SC) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1231 participants
  High

Intervention not reported

• Anti‐interleukin‐13 and anti‐interleukin‐4 agents versus placebo, anti‐interleukin‐5 or anti‐immunoglobulin‐E agents,… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 4829 participants
  Moderate

Tiotropium + LABA/ICS combination vs tiotropium

• Combination inhaled steroid and long‐acting beta₂‐agonist in addition to tiotropium versus tiotropium or combination… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 4 participants
  Moderate

Tiotropium + LABA/ICS combination vs tiotropium

• Combination inhaled steroid and long‐acting beta₂‐agonist in addition to tiotropium versus tiotropium or combination… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1 participants
  Moderate

ICS + LAMA add‐on vs ICS dose increase

• Long‐acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus higher dose ICS for adults… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1 participants
  Moderate

Children: prednisolone vs dexamethasone

Children: prednisolone showed no clear difference in admission at initial presentation compared with dexamethasone (low certainty).

• Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
  OR 1.08 [0.74, 1.58]
  3 studies · 1007 participants
  Low

Vitamin D vs placebo

• Vitamin D for the management of asthma 2023 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 1286 participants
  High

CPAP with expiratory pressure relief vs fixed CPAP

• Pressure modification or humidification for improving usage of continuous positive airway pressure machines in adults… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 609 participants
  Low

CPAP with expiratory pressure relief vs fixed CPAP

The review found no eligible studies for this question.

• Pressure modification or humidification for improving usage of continuous positive airway pressure machines in adults… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CPAP with expiratory pressure relief vs fixed CPAP

• Pressure modification or humidification for improving usage of continuous positive airway pressure machines in adults… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 515 participants
  Moderate

CPAP with expiratory pressure relief vs fixed CPAP

CPAP with expiratory pressure relief showed no clear difference in withdrawals (parallel group trials/first arm cross‐over trials) compared with fixed CPAP (low certainty).

• Pressure modification or humidification for improving usage of continuous positive airway pressure machines in adults… 2019 · Cochrane Headline outcomes only
  OR 0.86 [0.48, 1.55]
  2 studies · 298 participants
  Low

CPAP with expiratory pressure relief vs fixed CPAP

• Pressure modification or humidification for improving usage of continuous positive airway pressure machines in adults… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 74 participants
  Low

CPAP with expiratory pressure relief vs fixed CPAP

• Pressure modification or humidification for improving usage of continuous positive airway pressure machines in adults… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 342 participants
  High

CPAP with expiratory pressure relief vs fixed CPAP

• Pressure modification or humidification for improving usage of continuous positive airway pressure machines in adults… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 577 participants
  Very low

Continuous positive airway pressure (CPAP) vs no CPAP

• Non‐invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive sleep apnoea 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 27 participants
  Very low
• Non‐invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive sleep apnoea 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 57 participants
  Very low