What do systematic reviews say?

Artemisia desertorum spreng (Shahaosan) vs Artemisia desertorum spreng (Yunnan)

Artemisia desertorum spreng (Shahaosan) showed no clear difference in presence of dry socket compared with artemisia desertorum spreng (Yunnan); GRADE not reported.

• Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes

  Follow-up: median 7 days
  RR 0.47 [0.04, 5.06]
  1 study · 178 participants
  GRADE not reported

Artemisia desertorum spreng (Yunnan) vs placebo

Artemisia desertorum spreng (Yunnan) showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.

• Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes

  Follow-up: median 7 days
  RR 0.28 [0.06, 1.28]
  1 study · 182 participants
  GRADE not reported

Artemisia desertorum spreng (Shahaosan) vs placebo

Artemisia desertorum spreng (Shahaosan) showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.

• Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes

  Follow-up: median 7 days
  RR 0.13 [0.02, 1.02]
  1 study · 188 participants
  GRADE not reported

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Chlorhexidine rinse (0.2%) pre- and post-extraction vs Chlorhexidine rinse (0.2%) post-extraction only

Chlorhexidine rinse (0.2%) pre- and post-extraction showed no clear difference in presence of dry socket compared with chlorhexidine rinse (0.2%) post-extraction only; GRADE not reported.

• Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes

  Follow-up: median 7 days
  RR 0.58 [0.15, 2.17]
  1 study · 99 participants
  GRADE not reported

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Chlorhexidine rinse (0.12% and 0.2%, pre- and post-extraction) vs placebo or no treatment

Chlorhexidine rinse (0.12% and 0.2%, pre- and post-extraction) probably leads to lower presence of dry socket compared with placebo or no treatment (moderate certainty).

• Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes

  Follow-up: median 7 days
  OR 0.38 [0.25, 0.58]
  6 studies · 1547 participants
  Moderate

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Chlorhexidine rinse (0.12% and 0.2%, pre- and post-extraction) vs placebo or no treatment

• Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes

  Follow-up: median 7 days
  3 trials reported no adverse events. 1 study reported adverse events (alterations in taste, bad taste, staining) in 24/62 in chlorhexidine group versus 0/40 in placebo group, Peto OR = 8.42 (95% CI 3.31 to 21.39). A…
  6 studies
  GRADE not reported

Subperiosteal prepared (SPP) wound closure after tooth extraction vs Epiperiosteal prepared (EPP) wound closure after tooth extraction

Subperiosteal prepared (SPP) wound closure after tooth extraction showed no clear difference in MRONJ after tooth extraction (incidence proportion) compared with epiperiosteal prepared (EPP) wound closure after tooth extraction (low certainty).

• Interventions for managing medication‐related osteonecrosis of the jaw 2022 · Cochrane All outcomes

  6 months
  RR 0.09 [0.00, 1.56]
  1 study · 132 participants
  Low

Absence (previous removal or agenesis) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

It is very uncertain whether absence (previous removal or agenesis) of asymptomatic disease-free… changes caries affecting the (distal) adjacent second molar compared with presence (retention) of asymptomatic disease-free impacted wisdom… (very low certainty).

• Surgical removal versus retention for the management of asymptomatic disease‐free impacted wisdom teeth 2020 · Cochrane All outcomes

  Follow-up 3 to over 25 years · Soft tissue impaction
  RR 1.20 [0.17, 9.10]
  1 study · 416 participants
  Very low
• Surgical removal versus retention for the management of asymptomatic disease‐free impacted wisdom teeth 2020 · Cochrane All outcomes

  Follow-up 3 to over 25 years · Bony impaction
  RR 0.69 [0.27, 1.82]
  1 study · 416 participants
  Very low

Absence (previous removal or agenesis) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

It is very uncertain whether absence (previous removal or agenesis) of asymptomatic disease-free… changes periodontitis (distal alveolar bone loss, adjacent second molar) compared with presence (retention) of asymptomatic disease-free impacted wisdom… (very low certainty).

• Surgical removal versus retention for the management of asymptomatic disease‐free impacted wisdom teeth 2020 · Cochrane All outcomes

  Follow-up 3 to over 25 years · Bony impaction
  RR 0.32 [0.19, 0.54]
  1 study · 416 participants
  Very low
• Surgical removal versus retention for the management of asymptomatic disease‐free impacted wisdom teeth 2020 · Cochrane All outcomes

  Follow-up 3 to over 25 years · Soft tissue impaction
  RR 0.11 [0.06, 0.22]
  1 study · 416 participants
  Very low

Absence (previous removal or agenesis) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

It is very uncertain whether absence (previous removal or agenesis) of asymptomatic disease-free… changes periodontitis (distal probing depth greater than 4 mm, adjacent… compared with presence (retention) of asymptomatic disease-free impacted wisdom… (very low certainty).

• Surgical removal versus retention for the management of asymptomatic disease‐free impacted wisdom teeth 2020 · Cochrane All outcomes

  Follow-up 3 to over 25 years · Soft tissue impaction
  RR 0.15 [0.07, 0.34]
  1 study · 416 participants
  Very low
• Surgical removal versus retention for the management of asymptomatic disease‐free impacted wisdom teeth 2020 · Cochrane All outcomes

  Follow-up 3 to over 25 years · Bony impaction
  RR 0.63 [0.37, 1.04]
  1 study · 416 participants
  Very low