Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

480 questions · 484 findings · 52 reviews · Musculoskeletal · Headline outcomes only

No studies found 114 · 23.6%GRADE not reported 24 · 5%Very low 33 · 6.8%Low 145 · 30%Moderate 116 · 24%High 52 · 10.7%

Certolizumab pegol 200 mg sc (with or without MTX) vs placebo (with or without MTX)

Acceptability: total withdrawals · patients with rheumatoid arthritis in adults

Certolizumab pegol 200 mg sc (with or without MTX) probably leads to lower all Withdrawals: All doses of certolizumab pegol vs placebo compared with placebo (with or without MTX) (moderate certainty).

1 finding from 1 review

Certolizumab pegol 200 mg sc (with or without MTX) vs placebo (with or without MTX)

Withdrawals due to adverse events · patients with rheumatoid arthritis in adults

Certolizumab pegol 200 mg sc (with or without MTX) leads to higher withdrawals due to adverse events All doses of certolizumab pegol… compared with placebo (with or without MTX) (high certainty).

1 finding from 1 review