Joint pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes joint pain at rest compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).
1 finding from 1 review
Patient discomfort · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Muscle pain when chewing · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes muscle pain when chewing compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).
1 finding from 1 review
Severity of joint noise · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes severity of joint noise compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).
1 finding from 1 review
Depression · People with temporomandibular disorders (TMD)
Occlusal splint led to lower depression compared with no treatment or placebo (non-occlusal or transparent-foil placebo…; GRADE not reported.
1 finding from 1 review
Frequency of joint noise · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes frequency of joint noise compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).
1 finding from 1 review
Range of mandibular motion · People with temporomandibular disorders (TMD)
Occlusal splint showed no clear difference in range of mandibular motion compared with no treatment or placebo (non-occlusal or transparent-foil placebo…; GRADE not reported.
1 finding from 1 review
Recurrence · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Self-reported joint pain when chewing · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes self-reported joint pain when chewing compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).
1 finding from 1 review
Muscle pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes muscle pain at rest compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).
1 finding from 1 review
Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
No adverse events were reported. Six trials (673 participants) reported no adverse events from the use of chlorhexidine gel; one study (Rubio-Palau 2015) reported gastrointestinal discomfort (30, 18%), dizziness (10,…
7 studies
GRADE not reported
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Tranexamic acid (AMCA cones) showed no clear difference in presence of dry socket compared with placebo (lactose cones); GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Apernyl (acetylsalicylic acid pellet) showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.
1 finding from 1 review
Healing of MRONJ · People with established (manifest) MRONJ
Teriparatide 20 microg daily in addition to standard care showed no clear difference in healing of MRONJ (resolution of lesions) compared with placebo in addition to standard care (low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
P-hydroxybenzoic acid showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine rinse (0.12% and 0.2%, pre- and post-extraction) probably leads to lower presence of dry socket compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Gaseous ozone showed no clear difference in presence of dry socket compared with placebo or control; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Artemisia desertorum spreng (Shahaosan) showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.
1 finding from 1 review
Duration of treatment (days) · Adults (>18 years) with established dry socket following permanent tooth extraction
Metronidazole (intrasocket) led to lower duration of treatment (days) compared with placebo; GRADE not reported.
1 finding from 1 review
Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
3 trials reported no adverse events. 1 study reported adverse events (alterations in taste, bad taste, staining) in 24/62 in chlorhexidine group versus 0/40 in placebo group, Peto OR = 8.42 (95% CI 3.31 to 21.39). A…
6 studies
GRADE not reported