Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Vascular

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 20%Moderate 4 · 80%High 0 · 0%

Phlebotonics vs placebo?

Oedema in the lower legs (dichotomous variable) · patients with venous insufficiency

Do phlebotonics improve signs and symptoms of venous insufficiency… probably leads to lower oedema in the lower legs (dichotomous variable) compared with placebo? (moderate certainty).

1 finding from 1 review

Phlebotonics for venous insufficiency 2020 · Cochrane Headline outcomes only
RR 0.7 [0.63, 0.78]
13 studies · 1245 participants
Moderate

Phlebotonics vs placebo?

Oedema in the lower legs (ankle circumference, mm) · patients with venous insufficiency

1 finding from 1 review

Phlebotonics for venous insufficiency 2020 · Cochrane Headline outcomes only
no estimate extracted
15 studies · 2010 participants
Moderate

Phlebotonics vs placebo?

QoL · patients with venous insufficiency

1 finding from 1 review

Phlebotonics for venous insufficiency 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1639 participants
Moderate

Phlebotonics vs placebo?

Ulcer healing · patients with venous insufficiency

Do phlebotonics improve signs and symptoms of venous insufficiency… showed no clear difference in ulcer healing (dichotomous variable) compared with placebo? (low certainty).

1 finding from 1 review

Phlebotonics for venous insufficiency 2020 · Cochrane Headline outcomes only
RR 0.94 [0.79, 1.13]
6 studies · 461 participants
Low

Phlebotonics vs placebo?

Adverse events · patients with venous insufficiency

Do phlebotonics improve signs and symptoms of venous insufficiency… probably leads to higher adverse events compared with placebo? (moderate certainty).

1 finding from 1 review

Phlebotonics for venous insufficiency 2020 · Cochrane Headline outcomes only
RR 1.14 [1.02, 1.27]
37 studies · 5789 participants
Moderate