Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

201 questions · 209 findings · 10 reviews · Common Mental Disorders

No studies found 69 · 33%GRADE not reported 1 · 0.5%Very low 69 · 33%Low 40 · 19.1%Moderate 23 · 11%High 7 · 3.3%

Propranolol vs placebo

Treatment efficacy CAPS, CIDI · adult participants (18 years and older) who have been exposed to any traumatic events, but who did not meet the diagnostic criteria for…

Propranolol showed no clear difference in treatment efficacy CAPS, CIDI compared with placebo (low certainty).

1 finding from 1 review

Hydrocortisone vs placebo

Treatment efficacy CAPS, SCID‐IV, PTSS‐10Q‐I · adult participants (18 years and older) who have been exposed to any traumatic events, but who did not meet the diagnostic criteria for…

Hydrocortisone probably leads to lower treatment efficacy CAPS, SCID‐IV, PTSS‐10Q‐I compared with placebo (moderate certainty).

1 finding from 1 review

New‐generation antidepressants vs placebo

Treatment response (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults

It is very uncertain whether new‐generation antidepressants changes treatment response (post‐treatment score on self report and… compared with placebo (very low certainty).

1 finding from 1 review

Natural products vs placebo

Treatment response (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults

It is very uncertain whether natural products changes treatment response (post‐treatment score on self report and… compared with placebo (very low certainty).

1 finding from 1 review

Tricyclic antidepressants vs another medication

Treatment response (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults

Tricyclic antidepressants showed no clear difference in treatment response (post‐treatment score on self report and… compared with another medication (low certainty).

1 finding from 1 review