Neonatal mortality · neonates with possible serious bacterial infection
Comparison 2: 2 days injectable benzylpenicillin + injectable… showed no clear difference in neonatal mortality compared with 7 days injectable benzylpenicillin + injectable gentamicin (low certainty).
1 finding from 1 review
Early neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Late neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Sepsis‐specific neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment failure · neonates with possible serious bacterial infection
Comparison 2: 2 days injectable benzylpenicillin + injectable… showed no clear difference in treatment failure compared with 7 days injectable benzylpenicillin + injectable gentamicin (moderate certainty).
1 finding from 1 review
Adverse events · neonates with possible serious bacterial infection
Comparison 2: 2 days injectable benzylpenicillin + injectable… showed no clear difference in adverse events compared with 7 days injectable benzylpenicillin + injectable gentamicin (moderate certainty).
1 finding from 1 review
All‐cause mortality maximum · neonates with early‐onset sepsis
It is very uncertain whether ampicillin plus gentamicin changes all‐cause mortality maximum compared with penicillin plus gentamicin (very low certainty).
1 finding from 1 review
All‐cause mortality maximum · neonates with early‐onset sepsis
1 finding from 1 review
Serious adverse events maximum · neonates with early‐onset sepsis
1 finding from 1 review
Serious adverse events maximum · neonates with early‐onset sepsis
It is very uncertain whether ampicillin plus gentamicin changes serious adverse events maximum compared with penicillin plus gentamicin (very low certainty).
1 finding from 1 review
Circulatory support maximum · neonates with early‐onset sepsis
It is very uncertain whether ampicillin plus gentamicin changes circulatory support maximum compared with penicillin plus gentamicin (very low certainty).
1 finding from 1 review
Neurological developmental impairment maximum · neonates with early‐onset sepsis
It is very uncertain whether ampicillin plus gentamicin changes neurological developmental impairment maximum compared with penicillin plus gentamicin (very low certainty).
1 finding from 1 review
Necrotising enterocolitis maximum · neonates with early‐onset sepsis
It is very uncertain whether ampicillin plus gentamicin changes necrotising enterocolitis maximum compared with penicillin plus gentamicin (very low certainty).
1 finding from 1 review
Neonatal mortality · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in neonatal mortality compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Treatment failure · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in treatment failure compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Adverse events · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in adverse events compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Neonatal mortality · neonates with possible serious bacterial infection
Comparison 2: 7 days oral amoxicillin + injectable gentamicin showed no clear difference in neonatal mortality compared with 7 days injectable benzylpenicillin + injectable gentamicin (moderate certainty).
1 finding from 1 review
Early neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Late neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Sepsis‐specific neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found