Pulmonary complications (as defined by study authors, including pneumonia, embolism, reduced pulmonary function, prolonged ventilation, and pleural effusion, during the index hospital admission) · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with cardiopulmonary bypass
Prophylactic corticosteroids may leads to lower pulmonary complications (as defined by study authors, including… compared with placebo or no corticosteroids (low certainty).
1 finding from 1 review
Cardiopulmonary bypass time · participants requiring aortic valve replacement
1 finding from 1 review
Harms: pulmonary embolus or DVT · adults with or without existing CVD
It is very uncertain whether high changes harms: pulmonary embolus or DVT compared with low alpha‐linolenic acid omega‐3 fats (very low certainty).
1 finding from 1 review
Harms: pulmonary embolus or DVT · adults with or without existing CVD
It is very uncertain whether high changes harms: pulmonary embolus or DVT compared with low long‐chain omega‐3 fats (very low certainty).
1 finding from 1 review
Non‐fatal cardiovascular events · patients with heart failure with sinus rhythm
Summary of findings: warfarin showed no clear difference in non‐fatal cardiovascular events (non‐fatal stroke, myocardial… compared with aspirin (moderate certainty).
1 finding from 1 review
Non‐fatal cardiovascular events · patients with heart failure with sinus rhythm
Summary of findings: warfarin showed no clear difference in non‐fatal cardiovascular events (non‐fatal stroke, myocardial… compared with clopidogrel (low certainty).
1 finding from 1 review
Pulmonary embolism · Post‐menopausal women with pre‐exisiting cardiovascular disease
Hormone therapy showed no clear difference in pulmonary embolism compared with placebo (moderate certainty).
1 finding from 1 review
Pulmonary embolism · Post‐menopausal women without prior cardiovascular disease
1 finding from 1 review
Intervention not reported
Positive xenodiagnosis: all populations ‐ RCT data ‐ nitroderivatives Xenodiagnosis · people with chronic asymptomatic Trypanosoma cruzi infection
The intervention leads to lower positive xenodiagnosis: all populations ‐ RCT data ‐… (high certainty).
1 finding from 1 review
Intervention not reported
Mean reduction of antibodies titres: all populations, all tested drugs Mean change of antibodies · people with chronic asymptomatic Trypanosoma cruzi infection
1 finding from 1 review
Mortality within the longest · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with cardiopulmonary bypass
Prophylactic corticosteroids showed no clear difference in all‐cause mortality (during the index hospital admission, or within… compared with placebo or no corticosteroids (low certainty).
1 finding from 1 review
Cardiac complications (as defined by study authors, including cardiac compromise and fatal and non‐fatal myocardial infarction, defined as ECG changes, echocardiological changes, or disproportionate elevation of troponins, during the index hospita... · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with cardiopulmonary bypass
Prophylactic corticosteroids may leads to higher cardiac complications (as defined by study authors, including… compared with placebo or no corticosteroids (low certainty).
1 finding from 1 review
Infectious complications · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with cardiopulmonary bypass
Prophylactic corticosteroids may leads to lower infectious complications (as defined by study authors, including… compared with placebo or no corticosteroids (low certainty).
1 finding from 1 review
Gastrointestinal bleeding · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with cardiopulmonary bypass
Prophylactic corticosteroids showed no clear difference in gastrointestinal (GI) bleeding (as defined by study authors,… compared with placebo or no corticosteroids (low certainty).
1 finding from 1 review
Renal failure · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with cardiopulmonary bypass
Prophylactic corticosteroids showed no clear difference in renal failure (as defined by study authors, including dialysis,… compared with placebo or no corticosteroids (low certainty).
1 finding from 1 review
Length of stay · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with cardiopulmonary bypass
1 finding from 1 review
Acute kidney injury · adults undergoing cardiac surgery with cardiopulmonary bypass
It is very uncertain whether high changes acute kidney injury compared with low blood pressure target (very low certainty).
1 finding from 1 review
Cognitive deterioration · adults undergoing cardiac surgery with cardiopulmonary bypass
High showed no clear difference in cognitive deterioration compared with low blood pressure target (low certainty).
1 finding from 1 review
All‐cause mortality · adults undergoing cardiac surgery with cardiopulmonary bypass
It is very uncertain whether high changes all‐cause mortality compared with low blood pressure target (very low certainty).
1 finding from 1 review
Quality of life · adults undergoing cardiac surgery with cardiopulmonary bypass
It is very uncertain whether high changes quality of life compared with low blood pressure target (very low certainty).
1 finding from 1 review