Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

35 questions · 35 findings · 5 reviews · Schizophrenia · Headline outcomes only

No studies found 3 · 8.6%GRADE not reported 11 · 31.4%Very low 12 · 34.3%Low 8 · 22.9%Moderate 1 · 2.9%High 0 · 0%

Switch to another antipsychotic vs antipsychotic cessation

Adverse effects: use of antiparkinsonism drugs · psychiatric patients (schizophrenia) with antipsychotic‐induced tardive dyskinesia

It is very uncertain whether switch to another antipsychotic changes adverse effects: use of antiparkinsonism drugs compared with antipsychotic cessation (very low certainty).

1 finding from 1 review

Switch to another antipsychotic vs antipsychotic cessation

Leaving the study early · psychiatric patients (schizophrenia) with antipsychotic‐induced tardive dyskinesia

It is very uncertain whether switch to another antipsychotic changes acceptability of the treatment: leaving the study early compared with antipsychotic cessation (very low certainty).

1 finding from 1 review

Switch to another antipsychotic vs antipsychotic cessation

Tardive dyskinesia: No clinically important improvement · psychiatric patients (schizophrenia) with antipsychotic‐induced tardive dyskinesia

Switch to another antipsychotic may leads to lower tardive dyskinesia: no clinically important improvement compared with antipsychotic cessation (low certainty).

1 finding from 1 review

Intervention not reported

Behaviour: occurrence of violent incidents (to self, others, or property) · people with primary delusional infestation
1 finding from 1 review

CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES

Mental state: General ‐ clinically important change (no improvement) · patients with schizophrenia

CBT showed no clear difference in mental state: General ‐ clinically important change (no improvement) compared with ALL OTHER PSYCHOLOGICAL THERAPIES (low certainty).

1 finding from 1 review

CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES

Satisfaction with treatment: leaving the study early Endpoint data (events) · patients with schizophrenia

CBT may leads to lower satisfaction with treatment ‐ leaving the study early for any reason compared with ALL OTHER PSYCHOLOGICAL THERAPIES (low certainty).

1 finding from 1 review

Anticholinergic medication vs other treatments

Adverse effect: any adverse effects · chronic schizophrenia patients with antipsychotic‐induced tardive dyskinesia

It is very uncertain whether anticholinergic medication changes adverse effect: any adverse effects compared with other treatments (very low certainty).

1 finding from 1 review

Anticholinergic medication vs other treatments

Leaving the study early · chronic schizophrenia patients with antipsychotic‐induced tardive dyskinesia

It is very uncertain whether anticholinergic medication changes acceptability of the treatment: leaving the study early compared with other treatments (very low certainty).

1 finding from 1 review

Anticholinergic medication vs other treatments

Tardive dyskinesia: No clinically important improvement · chronic schizophrenia patients with antipsychotic‐induced tardive dyskinesia

It is very uncertain whether anticholinergic medication changes tardive dyskinesia: Not improved to a clinically important extent compared with other treatments (very low certainty).

1 finding from 1 review