Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

34 questions · 40 findings · 3 reviews · Drugs and Alcohol

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 17 · 42.5%Low 19 · 47.5%Moderate 4 · 10%High 0 · 0%

Cognitive behavioural therapy and other therapies vs prison therapeutic community

Arrested for any crime at 6 months · summary findings of female review

It is very uncertain whether cognitive behavioural therapy and other therapies changes arrested for any crime at 6 months compared with prison therapeutic community (very low certainty).

1 finding from 1 review

Cognitive behavioural therapy and other therapies vs prison therapeutic community

Arrested (not parole violation) at 6 months · summary findings of female review

It is very uncertain whether cognitive behavioural therapy and other therapies changes arrested (not parole violation) at 6 months compared with prison therapeutic community (very low certainty).

1 finding from 1 review

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: baclofen versus clonidine compared with other pharmacological detoxification treatment (very low certainty).

4 findings from 1 review
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Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Withdrawal symptoms · management of opium withdrawal
4 findings from 1 review
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Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment: clonidine versus clonidine plus amantadine, inpatient setting · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus clonidine plus amantadine,… compared with other pharmacological detoxification treatment (very low certainty).

1 finding from 1 review

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment: clonidine versus buprenorphine, inpatient setting · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus buprenorphine, inpatient… compared with other pharmacological detoxification treatment (very low certainty).

1 finding from 1 review

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment: methadone versus methadone plus gabapentin · management of opium withdrawal

Pharmacological detoxification treatment showed no clear difference in completion of treatment: methadone versus methadone plus gabapentin compared with other pharmacological detoxification treatment (low certainty).

1 finding from 1 review

Mixed action antidepressant vs placebo

Participants with at least some Side Effects · cannabis dependence

Mixed action antidepressant showed no clear difference in participants experiencing adverse effects compared with placebo (low certainty).

1 finding from 1 review

Buspirone vs placebo

Abstinence · cannabis dependence

Buspirone showed no clear difference in participants abstinent at end of treatment compared with placebo (low certainty).

1 finding from 1 review

Buspirone vs placebo

Participants with at least some Side Effects · cannabis dependence

Buspirone showed no clear difference in participants experiencing adverse effects compared with placebo (low certainty).

1 finding from 1 review