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Evidence found and GRADE certainty

63 questions · 63 findings · 3 reviews · Pregnancy and Childbirth

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No studies found 7 · 11.1%GRADE not reported 0 · 0%Very low 24 · 38.1%Low 25 · 39.7%Moderate 7 · 11.1%High 0 · 0%

Oral misoprostol vs vaginal misoprostol

Uterine hyperstimulation with fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol may leads to lower uterine hyperstimulation with fetal heart rate changes compared with vaginal misoprostol (low certainty).

1 finding from 1 review

Oral misoprostol vs vaginal misoprostol

Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol may leads to lower uterine hyperstimulation without fetal heart rate changes compared with vaginal misoprostol (low certainty).

1 finding from 1 review

Oral misoprostol vs vaginal misoprostol

Admission to neonatal intensive care unit · women in the third trimester for induction of labour.

Oral misoprostol showed no clear difference in admission to neonatal intensive care unit compared with vaginal misoprostol (moderate certainty).

1 finding from 1 review

Oral misoprostol one‐ to two‐hourly vs oral misoprostol four‐ to six‐hourly

Vaginal birth within 24 hours · women in the third trimester for induction of labour with intact membranes

It is very uncertain whether oral misoprostol one‐ to two‐hourly changes vaginal birth within 24 hours compared with oral misoprostol four‐ to six‐hourly (very low certainty).

1 finding from 1 review

Oral misoprostol one‐ to two‐hourly vs oral misoprostol four‐ to six‐hourly

Caesarean section · women in the third trimester for induction of labour with intact membranes

It is very uncertain whether oral misoprostol one‐ to two‐hourly changes caesarean section compared with oral misoprostol four‐ to six‐hourly (very low certainty).

1 finding from 1 review

Oral misoprostol one‐ to two‐hourly vs oral misoprostol four‐ to six‐hourly

Oxytocin augmentation · women in the third trimester for induction of labour with intact membranes

It is very uncertain whether oral misoprostol one‐ to two‐hourly changes oxytocin augmentation compared with oral misoprostol four‐ to six‐hourly (very low certainty).

1 finding from 1 review

Oral misoprostol one‐ to two‐hourly vs oral misoprostol four‐ to six‐hourly

Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour with intact membranes

It is very uncertain whether oral misoprostol one‐ to two‐hourly changes uterine hyperstimulation without fetal heart rate changes compared with oral misoprostol four‐ to six‐hourly (very low certainty).

1 finding from 1 review

Oral misoprostol 20 µg hourly titrated vs oral misoprostol 25 µg two‐hourly static

Uterine hyperstimulation with fetal heart rate changes · induction of labour.

It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation with FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).

1 finding from 1 review

Oral misoprostol 20 µg hourly titrated vs oral misoprostol 25 µg two‐hourly static

Uterine hyperstimulation without fetal heart rate changes · induction of labour.

It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation without FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).

1 finding from 1 review

Oral misoprostol 20 µg hourly titrated vs oral misoprostol 25 µg two‐hourly static

Apgar score less than 7 at 5 minutes · induction of labour.

It is very uncertain whether oral misoprostol 20 µg hourly titrated changes apgar score less than 7 at 5 minutes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).

1 finding from 1 review