Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 4 · 57.1%Very low 0 · 0%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%

Complete response · patients with cutaneous disease in systemic lupus erythematosus

Oral ciclosporin showed no clear difference in primary outcome: complete clinical response compared with oral azathioprine (low certainty).

1 finding from 1 review

Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
RR 0.83 [0.46, 1.52]
1 study · 89 participants
Low

Primary outcome: partial clinical response · patients with cutaneous disease in systemic lupus erythematosus

1 finding from 1 review

Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Secondary outcome: clinical flare · patients with cutaneous disease in systemic lupus erythematosus

1 finding from 1 review

Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Secondary outcome: CLASI · patients with cutaneous disease in systemic lupus erythematosus

1 finding from 1 review

Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Secondary outcome: Dermatology Quality of Life measure · patients with cutaneous disease in systemic lupus erythematosus

1 finding from 1 review

Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Adverse events: severe · patients with cutaneous disease in systemic lupus erythematosus

Oral ciclosporin showed no clear difference in adverse events: severe compared with oral azathioprine (low certainty).

1 finding from 1 review

Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
RR 0.89 [0.48, 1.65]
1 study · 89 participants
Low

Adverse events: minor (hirsutism) · patients with cutaneous disease in systemic lupus erythematosus

Oral ciclosporin may leads to higher adverse events: minor (hirsutism) compared with oral azathioprine (low certainty).

1 finding from 1 review

Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
RR 9.83 [1.32, 72.95]
1 study · 89 participants
Low