Findings

What do systematic reviews say?

7 questions · 7 findings · 3 reviews

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No studies found 1 · 14.3%GRADE not reported 2 · 28.6%Very low 1 · 14.3%Low 2 · 28.6%Moderate 0 · 0%High 1 · 14.3%

Optical coherence tomography (OCT) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…

1 finding from 1 review

Transillumination and optical coherence tomography for the detection and diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo; in vitro no limit if stored appropriately)
Sensitivity 0.94 [0.88, 0.97]
10 studies
GRADE not reported

Optical coherence tomography (OCT) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…

1 finding from 1 review

Transillumination and optical coherence tomography for the detection and diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo; in vitro no limit if stored appropriately)
Specificity 0.83 [0.68, 0.91]
10 studies
GRADE not reported

Transillumination and optical coherence tomography devices (all illumination devices combined: NIR, OCT, and FOTI/DIFOTI) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

1 finding from 1 review

Transillumination and optical coherence tomography for the detection and diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo; in vitro no limit if stored appropriately)
Specificity 0.87 [0.82, 0.92]
23 studies
Low

Transillumination and optical coherence tomography devices (all illumination devices combined: NIR, OCT, and FOTI/DIFOTI) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

1 finding from 1 review

Transillumination and optical coherence tomography for the detection and diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo; in vitro no limit if stored appropriately)
Sensitivity 0.75 [0.62, 0.85]
23 studies
Low

Vitamin A and fish oils (docosahexaenoic acid) vs placebo, vitamins, or no treatment

Optical coherence tomography (OCT) · retinitis pigmentosa

1 finding from 1 review

Vitamin A and fish oils for preventing the progression of retinitis pigmentosa 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 51 participants
Very low

Intervention not reported

Absence of fluid on optical coherence tomography (OCT) at 1 year · people with age‐related macular degeneration

The intervention showed no clear difference in absence of fluid on optical coherence tomography (OCT) at 1 year (high certainty).

1 finding from 1 review

Aflibercept for neovascular age‐related macular degeneration 2016 · Cochrane Headline outcomes only
RR 1.06 [0.98, 1.14]
2 studies · 2291 participants
High

Transillumination/OCT device used as an adjunct to a conventional visual examination vs Reference standard: histology, or enhanced visual examination with or without radiographs (also operative excavation, tooth separation, or microcomputed tomography)

Outcome not reported · Children or adults presenting asymptomatically or suspected of having enamel caries (clinical/in vivo studies); extracted teeth of…

The review found no eligible studies for this question.

1 finding from 1 review

Transillumination and optical coherence tomography for the detection and diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo; in vitro no limit if stored appropriately)
No studies formally reported the use of the illumination devices as an adjunct to a conventional visual examination, and therefore it has not been possible to make an assessment.
0 studies
No studies found