Question · asked by 1 review

Transillumination and optical coherence tomography devices (all illumination devices combined: NIR, OCT, and FOTI/DIFOTI) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation): Specificity for detection and diagnosis of early (enamel) caries

Population
Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or adults (in vitro studies); teeth apparently healthy or with suspected early caries. Studies intentionally including caries obviously into dentine or frank cavitation, or participants referred to secondary care for restorative treatment, were excluded. Target condition: early (non-cavitated enamel-only) coronal dental caries on occlusal, approximal, or smooth surfaces
Intervention
Transillumination and optical coherence tomography devices (all illumination devices combined: NIR, OCT, and FOTI/DIFOTI)
Comparison
Reference standard (histology, excavation, radiographs/microCT, or tooth separation)
Outcome
Specificity for detection and diagnosis of early (enamel) caries

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Transillumination and optical coherence tomography devices (all illumination devices combined: NIR, OCT, and FOTI/DIFOTI) vs Reference standard: histology, or enhanced visual examination with or without radiographs (also operative excavation, tooth separation, or microcomputed tomography)
Specificity for detection of enamel/early caries · Children or adults presenting asymptomatically or suspected of having enamel caries (clinical/in vivo studies);… · Up to 3 months between index test and reference standard (in vivo; in vitro no limit if stored appropriately)
Transillumination and optical coherence tomography for the detection and diagnosis of enamel caries (2021) · Cochrane All outcomes
Specificity 0.87 [0.82, 0.92]23 studiesLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Transillumination and optical coherence tomography for the detection and diagnosis of enamel caries
2021 · Cochrane All outcomes
2019-02-15Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.