Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

46 questions · 46 findings · 10 reviews · Vascular · Headline outcomes only

No studies found 9 · 19.6%GRADE not reported 2 · 4.3%Very low 15 · 32.6%Low 12 · 26.1%Moderate 7 · 15.2%High 1 · 2.2%

Intervention not reported

Heparin‐induced thrombocytopenia (HIT) · people undergoing surgical procedures and treated with UFH or LMWH for prophylaxis of thrombotic events lasting at least 5 days

The intervention may leads to lower heparin‐induced thrombocytopenia (HIT) (low certainty).

1 finding from 1 review

TNF‐α blockers intervention vs placebo or additional treatment

Adverse effects after treatment initiation: injection site reactions, neutropenia, infections, demyelinating disease, heart failure, malignancy, and induction of autoimmunity. · children diagnosed with Kawasaki disease

The review found no eligible studies for this question.

1 finding from 1 review

Emergency endovascular aneurysm repair vs conventional open repair

Short‐term mortality (30‐day or in‐hospital) · people diagnosed with RAAA

Emergency endovascular aneurysm repair showed no clear difference in short‐term mortality (30‐day or in‐hospital) compared with conventional open repair (moderate certainty).

1 finding from 1 review

Emergency endovascular aneurysm repair vs conventional open repair

Complication: renal complications (moderate or severe) (30‐day) · people diagnosed with RAAA

Emergency endovascular aneurysm repair showed no clear difference in complication: renal complications (moderate or severe) (30‐day) compared with conventional open repair (low certainty).

1 finding from 1 review