Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

105 questions · 106 findings · 16 reviews · Schizophrenia

No studies found 20 · 18.9%GRADE not reported 7 · 6.6%Very low 40 · 37.7%Low 23 · 21.7%Moderate 9 · 8.5%High 7 · 6.6%

SWITCHING ANTIPSYCHOTIC: TO OLANZAPINE vs MAINTENANCE RISPERIDONE/FGA

Leaving the study early · patients with sexual dysfunction due to antipsychotic drug therapy

It is very uncertain whether SWITCHING ANTIPSYCHOTIC: TO OLANZAPINE changes leaving the study early compared with MAINTENANCE RISPERIDONE/FGA (very low certainty).

1 finding from 1 review

Group B antipsychotic drugs: olanzapine + supportive intervention vs placebo or supportive treatment

Prodromal symptoms: transition to psychosis Endpoint data (events) · people in the prodromal stage of psychosis

It is very uncertain whether group B antipsychotic drugs: olanzapine + supportive intervention changes prodromal symptoms: transition to psychosis Endpoint data, (events)… compared with placebo + supportive intervention (very low certainty).

1 finding from 1 review

Group B antipsychotic drugs: olanzapine + supportive intervention vs placebo or supportive treatment

Satisfaction and acceptability of treatment (medium term) ‐ leaving the study early · people in the prodromal stage of psychosis

It is very uncertain whether group B antipsychotic drugs: olanzapine + supportive intervention changes satisfaction with treatment: leaving the study early Endpoint data… compared with placebo + supportive intervention (very low certainty).

1 finding from 1 review

Benzodiazepines vs antipsychotics

Global state: no improvement ‐ vs olanzapine ‐ medium term As defined in each study · psychosis‐induced aggression or agitation

It is very uncertain whether benzodiazepines changes global state: no improvement ‐ vs olanzapine ‐ medium term As… compared with antipsychotics (very low certainty).

1 finding from 1 review