All‐cause mortality · women with operable primary breast cancer
No axillary surgery showed no clear difference in all‐cause mortality compared with full axillary surgery (moderate certainty).
1 finding from 1 review
Locoregional recurrence · women with operable primary breast cancer
No axillary surgery probably leads to higher locoregional recurrence compared with full axillary surgery (moderate certainty).
1 finding from 1 review
Lymphoedema Increase in arm circumference · women with operable primary breast cancer
No axillary surgery may leads to lower lymphoedema Increase in arm circumference compared with full axillary surgery (low certainty).
1 finding from 1 review
Arm or shoulder movement impairment · women with operable primary breast cancer
It is very uncertain whether no axillary surgery changes arm or shoulder movement impairment compared with full axillary surgery (very low certainty).
1 finding from 1 review
Maxillary advancement (midfacial hard tissue change; Subspinale A-point) · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…
It is very uncertain whether maxillary distraction osteogenesis changes maxillary advancement (midfacial hard tissue change; Subspinale… compared with orthognathic surgery (conventional Le Fort I osteotomy) (very low certainty).
1 finding from 1 review
Long-term skeletal relapse/stability (horizontal movement of A-point) · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…
It is very uncertain whether maxillary distraction osteogenesis changes long-term skeletal relapse/stability (horizontal movement of A-point) compared with orthognathic surgery (conventional Le Fort I osteotomy) (very low certainty).
1 finding from 1 review
Speech: resonance (hypernasality) (deterioration/improvement) · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…
It is very uncertain whether maxillary distraction osteogenesis changes speech: resonance (hypernasality) (deterioration/improvement) compared with orthognathic surgery (conventional Le Fort I osteotomy) (very low certainty).
1 finding from 1 review
Clinical morbidities (adverse effects) · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…
1 finding from 1 review
SoF (Very Low): Clinical morbidities assessed with questionnaires, follow-up 12 months; risk with orthognathic surgery 3/14; risk with maxillary distraction osteogenesis 3/15; relative effect -; 29 participants (1…
1 study · 29 participants
Very low
Psychological status: social self-esteem (Culture-Free Self-Esteem Inventory subset); also general self-esteem and Social Avoidance and Distress Scale · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…
1 finding from 1 review
Results text (Ungraded; not in SoF): social self-esteem (subset of the Culture-Free Self-Esteem Inventory, CFSEI) - DO participants had lower social self-esteem in the first three months postoperatively, with a…
1 study · 30 participants
GRADE not reported
Midfacial soft tissue changes (facial profile landmarks: pronasale, subnasale, stomion superius, labrale superius) · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…
Maxillary distraction osteogenesis showed no clear difference in midfacial soft tissue changes (facial profile landmarks: pronasale,… compared with orthognathic surgery (conventional Le Fort I osteotomy); GRADE not reported.
1 finding from 1 review
Results text (Ungraded; not in SoF): both groups showed notable positive soft tissue changes of the upper lip and nose after maxillary advancement (39 participants). Between-group soft tissue differences at 2 years…
1 study · 39 participants
GRADE not reported
Velopharyngeal function (complete velopharyngeal closure; deterioration/improvement) · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…
It is very uncertain whether maxillary distraction osteogenesis changes velopharyngeal function (complete velopharyngeal closure;… compared with orthognathic surgery (conventional Le Fort I osteotomy) (very low certainty).
1 finding from 1 review
Psychological status: satisfaction with life (Satisfaction With Life Scale, SWLS) · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…
It is very uncertain whether maxillary distraction osteogenesis changes psychological status: satisfaction with life (Satisfaction With Life… compared with orthognathic surgery (conventional Le Fort I osteotomy) (very low certainty).
1 finding from 1 review
Speech: nasal emission · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…
Maxillary distraction osteogenesis showed no clear difference in speech: nasal emission compared with orthognathic surgery (conventional Le Fort I osteotomy); GRADE not reported.
1 finding from 1 review
All‐cause mortality · women with operable primary breast cancer
Axillary sampling showed no clear difference in all‐cause mortality compared with full axillary surgery (low certainty).
1 finding from 1 review
Local recurrence · women with operable primary breast cancer
Axillary sampling showed no clear difference in local recurrence compared with full axillary surgery (low certainty).
1 finding from 1 review
Time to readiness for surgery2 (minutes) · Adult patients undergoing hand, wrist or forearm surgery
1 finding from 1 review
Time to readiness for surgery2 (minutes) · Adult patients undergoing hand, wrist or forearm surgery
1 finding from 1 review
Time to readiness for surgery2 (minutes) · Adult patients undergoing hand, wrist or forearm surgery
1 finding from 1 review
Incidence of postoperativeseromaRR · people with breast and axillary surgery
Fibrin glue instillation under skin flaps showed no clear difference in incidence of postoperativeseromaRR compared with no‐fibrin (low certainty).
1 finding from 1 review
Mean volume of seromaSMD · people with breast and axillary surgery
1 finding from 1 review