Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

13 questions · 13 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 7.7%Low 8 · 61.5%Moderate 3 · 23.1%High 1 · 7.7%

Natriuretic peptide‐guided treatment vs usual care

Cardiovascular hospitalisation (as defined by trialists) · patients without heart failure

Natriuretic peptide‐guided treatment probably leads to lower cardiovascular hospitalisation (as defined by trialists) compared with standard care (moderate certainty).

1 finding from 1 review

Natriuretic peptide‐guided treatment vs usual care

Hospitalisation (any cause) · patients without heart failure

Natriuretic peptide‐guided treatment probably leads to lower all‐cause hospitalisation (all occurrences) compared with standard care (moderate certainty).

1 finding from 1 review

Natriuretic peptide‐guided treatment vs usual care

Ventricular dysfunction (as defined by trialists) · patients without heart failure

Natriuretic peptide‐guided treatment leads to lower ventricular dysfunction (as defined by trialists) compared with standard care (high certainty).

1 finding from 1 review

Does treatment guided by serial BNP or NT‐proBNP monitoring improve outcomes vs treatment guided by clinical assessment alone?

All‐cause mortality · patients with heart failure

Does treatment guided by serial BNP or NT‐proBNP monitoring improve… showed no clear difference in all‐cause mortality compared with treatment guided by clinical assessment alone? (low certainty).

1 finding from 1 review

Does treatment guided by serial BNP or NT‐proBNP monitoring improve outcomes vs treatment guided by clinical assessment alone?

Heart failure mortality · patients with heart failure

Does treatment guided by serial BNP or NT‐proBNP monitoring improve… showed no clear difference in heart failure mortality compared with treatment guided by clinical assessment alone? (low certainty).

1 finding from 1 review

Does treatment guided by serial BNP or NT‐proBNP monitoring improve outcomes vs treatment guided by clinical assessment alone?

Heart failure hospitalisation (RR) · patients with heart failure

Does treatment guided by serial BNP or NT‐proBNP monitoring improve… may leads to lower heart failure admissions compared with treatment guided by clinical assessment alone? (low certainty).

1 finding from 1 review

Does treatment guided by serial BNP or NT‐proBNP monitoring improve outcomes vs treatment guided by clinical assessment alone?

Hospital admissions · patients with heart failure

Does treatment guided by serial BNP or NT‐proBNP monitoring improve… showed no clear difference in all‐cause admissions compared with treatment guided by clinical assessment alone? (low certainty).

1 finding from 1 review