What do systematic reviews say?

NPPV vs SMC

NPPV may leads to lower HOSPITAL MORTALITY compared with SMC (low certainty).

• Non‐invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema 2019 · Cochrane Headline outcomes only
  RR 0.65 [0.51, 0.82]
  21 studies · 2484 participants
  Low

NPPV vs SMC

NPPV probably leads to lower ETI RATE compared with SMC (moderate certainty).

• Non‐invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema 2019 · Cochrane Headline outcomes only
  RR 0.49 [0.38, 0.62]
  20 studies · 2449 participants
  Moderate

NPPV vs SMC

NPPV showed no clear difference in ACUTE MI INCIDENCE compared with SMC (moderate certainty).

• Non‐invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema 2019 · Cochrane Headline outcomes only
  RR 1.03 [0.91, 1.16]
  5 studies · 1313 participants
  Moderate

NPPV vs SMC

• Non‐invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema 2019 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 1714 participants
  Very low

NPPV vs SMC

• Non‐invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema 2019 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 587 participants
  Very low

NPPV vs SMC

The review found no eligible studies for this question.

• Non‐invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPPV vs SMC

• Non‐invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema 2019 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 2038 participants
  Low

NPPV vs oxygen therapy

Noninvasive positive pressure ventilation (NPPV) showed no clear difference in hospital mortality compared with oxygen therapy (low certainty).

• Noninvasive positive pressure ventilation for acute respiratory failure following upper abdominal surgery 2015 · Cochrane Headline outcomes only
  RR 0.14 [0.01, 2.71]
  1 study · 209 participants
  Low

NPPV vs oxygen therapy

Noninvasive positive pressure ventilation (NPPV) may leads to lower rate of tracheal Intubation compared with oxygen therapy (low certainty).

• Noninvasive positive pressure ventilation for acute respiratory failure following upper abdominal surgery 2015 · Cochrane Headline outcomes only
  RR 0.25 [0.08, 0.83]
  2 studies · 269 participants
  Low

NPPV vs oxygen therapy

It is very uncertain whether noninvasive positive pressure ventilation (NPPV) changes ICU length of stay compared with oxygen therapy (very low certainty).

• Noninvasive positive pressure ventilation for acute respiratory failure following upper abdominal surgery 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 269 participants
  Very low