Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 11 findings · 1 reviews · Dental caries

No studies found 0 · 0%GRADE not reported 10 · 90.9%Very low 0 · 0%Low 0 · 0%Moderate 1 · 9.1%High 0 · 0%

Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline

Development of any (cavitated or non-cavitated) carious lesion · Children younger than 6 years with caries-free primary dentition (no cavitated or non-cavitated lesions at baseline)

Preschool children with mutans streptococci at baseline probably have about four times higher odds of developing early childhood caries (OR 4.13; moderate certainty).

10 findings from 1 review
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Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline

Future caries experience (dmft/dmfs) · Children younger than 6 years with caries-free primary dentition (no cavitated or non-cavitated lesions at baseline)

Children with mutans streptococci at baseline had a greater future caries experience (SMD 0.85, a large effect; ungraded).

1 finding from 1 review