Muscle relaxant vs control
Pain ‐ 24hrs (Single dose) · patients with pain management in rheumatoid arthritis
1 finding from 1 review
- no estimate extracted3 studies · 104 participantsLow
Findings
What do systematic reviews say?
15 questions · 15 findings · 3 reviews
No studies found 0 · 0%GRADE not reported 2 · 13.3%Very low 7 · 46.7%Low 6 · 40%Moderate 0 · 0%High 0 · 0%
Muscle relaxant vs control
Pain ‐ 1‐2 weeks · patients with pain management in rheumatoid arthritis
1 finding from 1 review
- no estimate extracted3 studies · 104 participantsVery low
Muscle relaxant vs control
Withdrawals due to adverse events · patients with pain management in rheumatoid arthritis
It is very uncertain whether muscle relaxant changes withdrawal due to Adverse Events compared with control (very low certainty).
1 finding from 1 review
- RR 2.84 [0.31, 26.08]5 studies · 180 participantsVery low
Muscle relaxant vs control
Total Number of Adverse Events ‐ only studies >24hrs duration · patients with pain management in rheumatoid arthritis
It is very uncertain whether muscle relaxant changes total Number of Adverse Events ‐ only studies >24hrs duration compared with control (very low certainty).
1 finding from 1 review
- RR 4.03 [1.08, 15.1]2 studies · 74 participantsVery low
Muscle relaxant vs control
Total Number of Adverse Events ‐ single dose studies · patients with pain management in rheumatoid arthritis
It is very uncertain whether muscle relaxant changes total Number of Adverse Events ‐ single dose studies compared with control (very low certainty).
1 finding from 1 review
- RR 1.4 [0.58, 3.41]3 studies · 106 participantsVery low
Muscle relaxant vs control
CNS adverse events · patients with pain management in rheumatoid arthritis
It is very uncertain whether muscle relaxant changes CNS adverse events compared with control (very low certainty).
1 finding from 1 review
- RR 5.96 [1.77, 20.08]2 studies · 74 participantsVery low
Oral cyclobenzaprine (muscle relaxant) vs placebo
Jaw pain (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral cyclobenzaprine (muscle relaxant) showed no clear difference in jaw pain (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
- Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes3 weeksMD -1.30 [-2.67, 0.07]1 study · 41 participantsGRADE not reported
Oral cyclobenzaprine (muscle relaxant) vs placebo
Adverse events (reported; mild, no withdrawals) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review
- Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes3 weeksHerman et al 2002 (cyclobenzaprine) reported adverse effects. Per the review's Adverse effects of interventions section: 'All but one study (Lobo et al 2004) reported adverse effects. Most of the reported adverse…1 study · 41 participantsGRADE not reported
Lidocaine vs placebo
Incidence of pain with lidocaine pretreatment Pain scales · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide
Lidocaine may leads to lower pain ‐ lidocaine compared with placebo (low certainty).
1 finding from 1 review
- Pharmacological and non‐pharmacological interventions for reducing rocuronium bromide induced pain on injection in… 2016 · Cochrane Headline outcomes onlyRR 0.23 [0.17, 0.31]29 studies · 2256 participantsLow
Fentanyl vs placebo
Pain ‐ fentanyl · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide
Fentanyl may leads to lower pain ‐ fentanyl compared with placebo (low certainty).
1 finding from 1 review
- Pharmacological and non‐pharmacological interventions for reducing rocuronium bromide induced pain on injection in… 2016 · Cochrane Headline outcomes onlyRR 0.42 [0.26, 0.7]7 studies · 514 participantsLow
Summary of findings table ‐ Remifentanil vs placebo
Pain ‐ remifentanil · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide
Remifentanil may leads to lower pain ‐ remifentanil compared with placebo (low certainty).
1 finding from 1 review
- Pharmacological and non‐pharmacological interventions for reducing rocuronium bromide induced pain on injection in… 2016 · Cochrane Headline outcomes onlyRR 0.1 [0.04, 0.26]7 studies · 494 participantsLow
Adverse effects of pharmacological intervention vs control
Breath holding · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide
It is very uncertain whether adverse effects of pharmacological intervention changes breath holding compared with control (very low certainty).
1 finding from 1 review
- Pharmacological and non‐pharmacological interventions for reducing rocuronium bromide induced pain on injection in… 2016 · Cochrane Headline outcomes onlyRR 1.19 [0.12, 11.65]2 studies · 279 participantsVery low
Adverse effects of pharmacological intervention vs control
Chest tightness · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide
It is very uncertain whether adverse effects of pharmacological intervention changes chest tightness compared with control (very low certainty).
1 finding from 1 review
- Pharmacological and non‐pharmacological interventions for reducing rocuronium bromide induced pain on injection in… 2016 · Cochrane Headline outcomes onlyRR 2.61 [0.12, 56.03]1 study · 90 participantsVery low
Adverse effects of pharmacological intervention vs control
Cough · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide
Adverse effects of pharmacological intervention may leads to higher cough compared with control (low certainty).
1 finding from 1 review
- Pharmacological and non‐pharmacological interventions for reducing rocuronium bromide induced pain on injection in… 2016 · Cochrane Headline outcomes onlyRR 9 [2.77, 29.29]5 studies · 529 participantsLow
Adverse effects of pharmacological intervention vs control
Adverse effects: pain on injection (solution deposition), Heft-Parker VAS 0-170 mm · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide
Adverse effects of pharmacological intervention showed no clear difference in pain on injection compared with control (low certainty).
1 finding from 1 review
- Pharmacological and non‐pharmacological interventions for reducing rocuronium bromide induced pain on injection in… 2016 · Cochrane Headline outcomes onlyRR 0.47 [0.09, 2.46]1 study · 118 participantsLow