Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

26 questions · 52 findings · 8 reviews · Oral Health

No studies found 0 · 0%GRADE not reported 42 · 80.8%Very low 7 · 13.5%Low 3 · 5.8%Moderate 0 · 0%High 0 · 0%

Breastfeeding for more than 24 months vs Not breastfed at the same age or breastfed for a shorter duration

Early childhood caries (ECC) - incidence/risk · Children with exclusively primary dentition (age ≤71 months)

Breastfeeding beyond 24 months is associated with an increased risk (incidence) of early childhood caries versus not breastfeeding at the same age (RR 2.44, 95% CI 1.97 to 3.02; low certainty).

1 finding from 1 review

High-frequency sugar consumption (three or more times daily) vs Low sugar intake (fewer than three times daily)

Early childhood caries experience (mean dmft) · Nigerian children with primary dentition (approximately 6 months to 5 years)

In primary dentition, high-frequency sugar consumption was associated with slightly higher, non-significant odds of caries (OR 1.13, 95% CI 0.23 to 5.44), with high heterogeneity (I2=83%; ungraded).

1 finding from 1 review

High-frequency sugar consumption (three or more times daily) vs Low sugar intake (fewer than three times daily)

Dental caries in permanent teeth · Nigerian individuals with permanent dentition (approximately 12 years and older)

In permanent dentition, high-frequency sugar consumption was associated with non-significant 15% higher odds of caries (OR 1.15, 95% CI 0.88 to 1.52), with no heterogeneity (I2=0%; ungraded).

1 finding from 1 review

High-frequency sugar consumption (three or more times daily) vs Low sugar intake (fewer than three times daily)

Dental caries prevalence · Nigerian individuals, including children and adults, with primary or permanent dentition

High-frequency sugar consumption was associated with 18% higher but non-significant odds of dental caries in Nigeria (OR 1.18, 95% CI 0.87 to 1.59; I2=36%; ungraded).

1 finding from 1 review

Partial pulpotomy with permanent restoration after more than 14 days vs No comparator

Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure

Permanent restoration after more than 14 days was associated with a pooled success rate of 23.2%.

1 finding from 1 review

Primary school-based interventions (one or more of: school health policy, oral health education, healthy school environment, access to oral health services, community involvement) vs usual practice

Plaque index (PI) / oral hygiene · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)

School-based interventions may reduce dental plaque scores (SMD -0.32, favouring intervention), but the certainty of evidence is very low.

1 finding from 1 review

Primary school-based interventions (one or more of: school health policy, oral health education, healthy school environment, access to oral health services, community involvement) vs usual practice

Oral hygiene measured by mean gingival scores · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)

The effect of school-based interventions on gingival scores is uncertain and not statistically significant (SMD 0.12; very low certainty).

1 finding from 1 review

Primary school-based interventions (one or more of: school health policy, oral health education, healthy school environment, access to oral health services, community involvement) vs usual practice

Dental caries · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)

Among children aged 6-8 years, DMFT scores were significantly reduced (SMD -0.11); subgroup not separately GRADE-rated.

8 findings from 1 review
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Primary school-based interventions (one or more of: school health policy, oral health education, healthy school environment, access to oral health services, community involvement) vs usual practice

Annual increment in DMFS (D3) · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)

Oral-health-education interventions significantly reduced net increment in DMFS (SMD -1.05); no significant subgroup difference vs other interventions (P=0.74).

5 findings from 1 review
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Primary school-based interventions (one or more of: school health policy, oral health education, healthy school environment, access to oral health services, community involvement) vs usual practice

Dental caries prevalence measured by dmft or DMFT/S score greater than one · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)

School-based interventions may reduce the prevalence of dental caries (RR 0.70, favouring intervention), but the certainty of evidence is very low.

3 findings from 1 review

Primary school-based interventions (one or more of: school health policy, oral health education, healthy school environment, access to oral health services, community involvement) vs usual practice

Caries increment, tooth index D(M)FT · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)

Among children aged 5-8 years, net increment in DMFT was not significantly reduced (SMD -0.36); no significant subgroup difference by age.

3 findings from 1 review

Laser fluorescence (DIAGNOdent 2190/pen) vs Reference standard

More advanced caries lesion detection · Primary teeth with approximal surfaces

Pooled specificity was reported, but the numerical estimate is not stated in the supplied text or attached figures; I²=89%; no GRADE rating was reported.

2 findings from 1 review

Laser fluorescence (DIAGNOdent 2190/pen) vs Reference standard

More advanced caries lesion detection · Permanent teeth with occlusal surfaces

Pooled sensitivity was reported, but the numerical estimate is not stated in the supplied text or attached figures; I²=73%; no GRADE rating was reported.

2 findings from 1 review

Laser fluorescence (DIAGNOdent 2190/pen) vs Reference standard

More advanced caries lesion detection · Permanent teeth with approximal surfaces

Pooled specificity was reported, but the numerical estimate is not stated in the supplied text or attached figures; I²=84%; no GRADE rating was reported.

2 findings from 1 review

Laser fluorescence (DIAGNOdent 2190/pen) vs Reference standard

More advanced caries lesion detection · Primary teeth with occlusal surfaces

Pooled specificity was reported, but the numerical estimate is not stated in the supplied text or attached figures; I²=31%; no GRADE rating was reported.

2 findings from 1 review

Fluorescence camera (FC) vs Reference standard

More advanced caries lesion detection · Primary teeth with occlusal surfaces

Pooled specificity was reported, but the numerical estimate is not stated in the supplied text or attached figures; I²=80%; no GRADE rating was reported.

2 findings from 1 review

Laser fluorescence (LF; DIAGNOdent) vs Reference standard

More advanced caries lesion detection · Permanent teeth with occlusal surfaces

Pooled specificity was reported, but the numerical estimate is not stated in the supplied text or attached figures; I²=77%; no GRADE rating was reported.

2 findings from 1 review