Intervention not reported
Cramp intensity (moderate or worse at 4 weeks) · pregnant women with leg cramps
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
10 questions · 11 findings · 6 reviews · Neuromuscular · Headline outcomes only
No studies found 1 · 9.1%GRADE not reported 1 · 9.1%Very low 4 · 36.4%Low 2 · 18.2%Moderate 3 · 27.3%High 0 · 0%
Intervention not reported
Cramp intensity (moderate or worse at 4 weeks) · for effects on cramps, people (other than pregnant women) with muscle cramps (largely older adults); for adverse events, all populations
The intervention showed no clear difference in cramp intensity (moderate or worse at 4 weeks) (moderate certainty).
1 finding from 1 review
- RR 1.33 [0.81, 2.21]2 studies · 91 participantsModerate
Botulinum toxin plus conservative treatment vs conservative treatment
Recurrence of ITW post‐treatment Assessed by improvement in toe walking based on Gait Analysis Classification An increase indicates improvement (an improvement indicated by a change in downgrading of the severe or 3, moderate or 2, and mild or 1 c... · children with ITW gait
1 finding from 1 review
- no estimate extracted1 study · 46 participantsVery low
Absorbable vs non‐absorbable sutures
Postoperative pain: early pain (10 days postoperatively) VAS 0 to 10 Verbal reporting scale No pain‐mild pain‐moderate pain‐severe pain (converted to numerical scale (0 to 3, 3 to 6, 6 to 10)
2 findings from 1 review
- Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery 2018 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 137 participantsVery low
- Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery 2018 · Cochrane Headline outcomes onlyno estimate extracted1 study · 54 participantsVery low
Absorbable vs non‐absorbable sutures
Postoperative pain: late pain (6 weeks postoperatively) VAS 0 to 10 Verbal reporting scale No pain‐mild pain‐moderate pain‐severe pain (converted to numerical scale (0 to 3, 3 to 6, 6 to 10)
1 finding from 1 review
- Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery 2018 · Cochrane Headline outcomes onlyno estimate extracted4 studies · 175 participantsVery low
Quinine vs a quinine‐vitamin E combination (Q‐Vel)
Cramp intensity (on 3‐point scale; 1 = mild; 2 = moderate; 3 = severe) · patients with muscle cramps
1 finding from 1 review
- no estimate extracted3 studies · 510 participantsLow
Quinine vs placebo
Cramp intensity (on 3‐point scale; 1 = mild; 2 = moderate; 3 = severe) · patients with muscle cramps
1 finding from 1 review
- no estimate extracted7 studies · 666 participantsModerate
Quinine vs vitamin E
Cramp intensity (on 3‐point scale; 1 = mild; 2 = moderate; 3 = severe) · patients with muscle cramps
1 finding from 1 review
- no estimate extracted3 studies · 513 participantsModerate
Topiramate 200 to 400 mg vs placebo
Participant‐reported pain relief of 30% or greater · neuropathic pain (two studies found in painful diabetic neuropathy, and one in lumbar radiculopathy)
1 finding from 1 review
- no estimate extracted1 study · 317 participantsGRADE not reported
Intervention not reported
"Moderate" benefit At least 30% reduction in pain · painful diabetic neuropathy
1 finding from 1 review
- no estimate extracted715 participantsLow