Cochrane · systematic review · CD012363
Interventions for idiopathic toe walking
Caserta, AJ, Pacey, V, Fahey, MC, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
NeuromuscularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 33.3%Ungraded 0 · 0%Very low 4 · 66.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Botulinum toxin plus conservative treatment versus conservative treatment only
Population: children with ITW gait
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Improvement (greater than 50% of time spent) heel‐toe walking Measured by parents' perception of toe walking frequency more than 50% of the time. Botulinum toxin plus conservative treatment vs conservative treatment only | RR 1.21 [0.57, 2.55] | 1 study · 46 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Active range of motion of the ankle joint Botulinum toxin plus conservative treatment vs conservative treatment only | no estimate extracted | NR | No studies |
Change from baseline in passive ankle dorsiflexion range of movement Botulinum toxin plus conservative treatment vs conservative treatment only | no estimate extracted | 1 study · 47 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Pain Botulinum toxin plus conservative treatment vs conservative treatment only | no estimate extracted | NR | No studies |
Recurrence of ITW post‐treatment Assessed by improvement in toe walking based on Gait Analysis Classification An increase indicates improvement (an improvement indicated by a change in downgrading of the severe or 3, moderate or 2, and mild or 1 c... Botulinum toxin plus conservative treatment vs conservative treatment only | no estimate extracted | 1 study · 46 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Adverse events Botulinum toxin plus conservative treatment vs conservative treatment only | no estimate extracted | 1 study · 47 participants | Very low Downgraded: risk of bias, imprecision, indirectness |