Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

30 questions · 42 findings · 11 reviews · Gynaecology and Fertility · Headline outcomes only

No studies found 1 · 2.4%GRADE not reported 3 · 7.1%Very low 12 · 28.6%Low 17 · 40.5%Moderate 8 · 19%High 1 · 2.4%

Summary of findings table ‐ Progestogens vs GnRH antagonists

Moderate or severe OHSS ‐ Normoresponders ‐ Donor oocytes ‐ Early phase stimulation protocol ‐ Fresh embryo transfer (MPA 10 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH agonist

Moderate or severe OHSS · assisted reproduction technology cycles

It is very uncertain whether summary of findings table ‐ Progestagen changes moderate or severe OHSS compared with gnRH agonist (very low certainty).

1 finding from 1 review

Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol

OHSS · Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures

Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only showed no clear difference in OHSS rate (mild, moderate or severe) per woman compared with monitoring with TVUS plus serum estradiol (low certainty).

1 finding from 1 review

Oestrogen therapy alone vs placebo

Venous thrombo‐embolism (DVT or PE): CEE 0.625 mg (moderate dose) · relatively healthy postmenopausal women

Oestrogen‐only hormone therapy (HT) showed no clear difference in venous thromboembolism (DVT or PE): CEE 0.625 mg (moderate dose) compared with placebo (moderate certainty).

1 finding from 1 review