Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,155 questions · 1,191 findings · 195 reviews · Headline outcomes only

No studies found 209 · 17.5%GRADE not reported 51 · 4.3%Very low 256 · 21.5%Low 273 · 22.9%Moderate 284 · 23.8%High 118 · 9.9%

Moderate vs low protein concentration of human milk fortifier

Mortality during period of therapy · preterm infants

Moderate showed no clear difference in mortality during the intervention period compared with low protein concentration of human milk fortifier; GRADE not reported.

1 finding from 1 review

Tight‐moderate vs loose glycaemic control (infant outcomes)

Large‐for‐gestational age · pregnant women with pre‐existing type 1 diabetes

Tight‐moderate may leads to lower large‐for‐gestational age (birthweight > 90th centile) compared with loose glycaemic control (infant outcomes) (low certainty).

1 finding from 1 review