Question · asked by 1 review

Tight‐moderate vs loose glycaemic control (infant outcomes): Perinatal mortality

Population
pregnant women with pre‐existing type 1 diabetes
Intervention
Tight‐moderate
Comparison
loose glycaemic control (infant outcomes)
Outcome
Perinatal mortality

It is very uncertain whether tight‐moderate changes perinatal mortality compared with loose glycaemic control (infant outcomes) (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Tight‐moderate vs loose glycaemic control (infant outcomes)
Perinatal mortality · pregnant women with pre‐existing type 1 diabetes
It is very uncertain whether tight‐moderate changes perinatal mortality compared with loose glycaemic control (infant outcomes) (very low certainty).
Different intensities of glycaemic control for pregnant women with pre‐existing diabetes (2016) · Cochrane Headline outcomes only
RR 0.07 [0, 1.37]1 study · 60 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Different intensities of glycaemic control for pregnant women with pre‐existing diabetes
2016 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.