Improvement in pain score (up to nine months after treatment): progesterone versus placebo · women with chronic pelvic pain
Medical treatment probably leads to higher improvement in pain score at end of treatment: progesterone versus… compared with placebo (moderate certainty).
2 findings from 1 review
Weight gain · women with chronic pelvic pain
Medical treatment leads to higher weight gain: progesterone versus placebo compared with placebo (high certainty).
1 finding from 1 review
Bloatedness: progesterone versus placebo · women with chronic pelvic pain
Medical treatment leads to higher bloatedness: progesterone versus placebo compared with placebo (high certainty).
1 finding from 1 review
Peto OR 3.2 [1.37, 7.47]
85 participants
High
Improvement in pain score: lofexidine versus placebo · women with chronic pelvic pain
Medical treatment showed no clear difference in improvement in pain score: lofexidine versus placebo compared with placebo (low certainty).
1 finding from 1 review
Drowsiness/lethargy: lofexidine versus placebo · women with chronic pelvic pain
Medical treatment probably leads to higher drowsiness/lethargy: lofexidine versus placebo compared with placebo (moderate certainty).
1 finding from 1 review
Dry mouth (xerostomia) · women with chronic pelvic pain
Medical treatment probably leads to higher dry mouth: lofexidine versus placebo compared with placebo (moderate certainty).
1 finding from 1 review
Uterine volume (cm³) · women with uterine fibroids
1 finding from 1 review
Operating time · women with uterine fibroids
3 findings from 1 review
no estimate extracted
6 studies · 443 participants
Very low
no estimate extracted
1 study · 39 participants
Low
no estimate extracted
6 studies · 617 participants
Low
Intraoperative blood loss (mL) · women with uterine fibroids
3 findings from 1 review
Blood transfusion · women with uterine fibroids
GnRHa treatment showed no clear difference in blood transfusions compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).
3 findings from 1 review
Overall postoperative morbidity · women with uterine fibroids
GnRHa treatment showed no clear difference in postoperative morbidity compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).
3 findings from 1 review
Uterine volume (cm³) · women with uterine fibroids
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Fibroid volume (cm³) · women with uterine fibroids
1 finding from 1 review
Fibroid volume (cm³) · women with uterine fibroids
1 finding from 1 review
Haemoglobin (g/dL) · women with uterine fibroids
1 finding from 1 review
Preoperative bleeding: (PBAC < 75) ulipristal acetate 5 mg · women with uterine fibroids
GnRHa treatment showed no clear difference in preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal… compared with other medical therapies before any surgery (moderate certainty).
1 finding from 1 review
Preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal acetate 10 mg · women with uterine fibroids
GnRHa treatment showed no clear difference in preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal… compared with other medical therapies before any surgery (moderate certainty).
1 finding from 1 review
Adverse events (hot flushes) · women with uterine fibroids
GnRHa treatment may leads to higher adverse events (hot flushes) compared with other medical therapies before any surgery (low certainty).
1 finding from 1 review
Haemoglobin (g/dL) · women with uterine fibroids
1 finding from 1 review
Preoperative bleeding · women with uterine fibroids
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found