Access to oral healthcare (referral pathways, documentation processes, operating efficiencies, staffing, visits for oral health issues, uptake of fluoride varnish/other preventive treatment, and visits to an oral health professional) · People of all ages and abilities served through primary care and related settings (children, pregnant women, older adults in…
Most strategies to integrate oral health into primary care were associated with improved access to oral healthcare (19 studies, narrative synthesis; ungraded).
1 finding from 1 review
Strategies to integrate oral health into primary care: a systematic review. 2023 All outcomesPrimary care, community, school, and aged-care/residential/nursing-home settings
Access to oral healthcare was the primary outcome most studied (n=19). Most studies reported results favouring the integration strategy, including improvements in referral pathways, documentation processes, operating…
19 studies
GRADE not reported
Lactobacillus count (pre- vs post-treatment) · Medically healthy individuals (adults and children, 6-60 years)
Placebo rinse did not significantly change Lactobacillus counts relative to baseline; not GRADE-rated.
1 finding from 1 review
Lactobacillus count (pre- vs post-treatment) · Medically healthy individuals (adults and children, 6-60 years)
Salvadora persica rinse reduced Lactobacillus counts relative to baseline; not GRADE-rated.
1 finding from 1 review
Streptococcus mutans count · Medically healthy individuals (adults and children, 6-60 years)
Salvadora persica rinse reduced Streptococcus mutans counts relative to baseline; not GRADE-rated.
1 finding from 1 review
Plaque · Medically healthy individuals (adults and children, 6-60 years)
Placebo rinse did not significantly change plaque relative to baseline; not GRADE-rated.
1 finding from 1 review
Plaque · Medically healthy individuals (adults and children, 6-60 years)
0.12% chlorhexidine rinse reduced plaque relative to baseline; not GRADE-rated.
1 finding from 1 review
Plaque · Medically healthy individuals (adults and children, 6-60 years)
Salvadora persica rinse reduced plaque relative to its own baseline; not GRADE-rated.
1 finding from 1 review
Streptococcus mutans count · Medically healthy individuals (adults and children, 6-60 years)
Placebo rinse did not significantly change Streptococcus mutans counts relative to baseline; not GRADE-rated.
1 finding from 1 review
Plaque · Medically healthy individuals (adults and children, 6-60 years)
0.2% chlorhexidine rinse reduced plaque relative to baseline; not GRADE-rated.
1 finding from 1 review
Service use: Emergency medical/dental treatment · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
The review found no eligible studies for this question.
1 finding from 1 review
Service use: Emergency medical/dental treatment · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
The review found no eligible studies for this question.
1 finding from 1 review
Service use: Emergency medical/dental treatment · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
The review found no eligible studies for this question.
1 finding from 1 review
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months) · topical urea 10%
Topical urea 10% (Alvarenga da Silva 2014) contributes to the topical treatments short-term symptom-relief comparison (insufficient/contradictory); no separate estimate reported.
1 study · 38 participants
GRADE not reported
Change in feeling of dryness · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months) · topical urea 10%
SoF9. Change in feeling of dryness short-term (xerostomia questionnaire, 1-5, lower better): single study narratively reported no difference before or after treatment; 38 participants (1 RCT, topical urea); very low.
1 study · 38 participants
Very low
Change in taste · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months) · topical urea 10%
SoF9. Change in taste short-term (Quantitative Sensory Testing gustative threshold): single study narratively reported no difference in short-term gustation thresholds; 38 participants (1 RCT, topical urea); very low.
1 study · 38 participants
Very low
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
2 findings from 1 review
Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months) · capsaicin oral rinse
Capsaicin oral rinse (Marino 2010; Silvestre 2012) contributes to the topical treatments short-term symptom-relief comparison (insufficient/contradictory). Silvestre 2012 data not presented due to 23% first-phase…
1 study
GRADE not reported
Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomeslong-term (>3 to 6 months) · capsaicin oral rinse
MD -2.60 [-5.11, -0.09]
1 study · 18 participants
Very low
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months) · benzydamine hydrochloride
SoF9 Topical treatments vs placebo. Symptom relief short-term: insufficient or contradictory evidence regarding benefit of any evaluated topical treatment; 150 participants (4 RCTs); very low. Subgroups: benzydamine (1…
4 studies · 150 participants
Very low
Adverse effects · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether topical treatments (lactoperoxidase oral rinse / Biotene) changes relief of burning/discomfort (symptom relief; pain intensity) compared with placebo (very low certainty).
1 finding from 1 review
Lactobacillus count (CFU/mL) · Medically healthy individuals (adults and children, 6-60 years)
Salvadora persica rinse reduced Lactobacillus counts more than placebo (favours Salvadora persica); not GRADE-rated.
1 finding from 1 review