Findings

What do systematic reviews say?

510 questions · 533 findings · 60 reviews

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No studies found 153 · 28.7%GRADE not reported 18 · 3.4%Very low 134 · 25.1%Low 123 · 23.1%Moderate 80 · 15%High 25 · 4.7%

Medical treatment vs placebo

Maternal opinion of treatment · women with breast engorgement

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for breast engorgement during lactation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Medical treatment vs placebo

Improvement in pain score (up to nine months after treatment): progesterone versus placebo · women with chronic pelvic pain

Medical treatment probably leads to higher improvement in pain score at end of treatment: progesterone versus… compared with placebo (moderate certainty).

2 findings from 1 review

Non‐surgical interventions for the management of chronic pelvic pain 2014 · Cochrane Headline outcomes only
Peto OR 3 [1.7, 5.31]
204 participants
Moderate
Non‐surgical interventions for the management of chronic pelvic pain 2014 · Cochrane Headline outcomes only
Peto OR 2.09 [1.18, 3.71]
204 participants
Moderate

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Death or stroke · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment probably leads to higher death or stroke compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis 2023 · Cochrane Headline outcomes only
RR 2.93 [1.81, 4.75]
4 studies · 989 participants
Moderate

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Long‐term ipsilateral stroke · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment probably leads to higher ipsilateral stroke compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis 2023 · Cochrane Headline outcomes only
RR 3.26 [1.94, 5.48]
4 studies · 989 participants
Moderate

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Type of recurrent event · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment showed no clear difference in type of recurrent event compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis 2023 · Cochrane Headline outcomes only
RR 0.79 [0.3, 2.07]
3 studies · 344 participants
Moderate

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Death · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment may leads to higher death compared with conventional medical treatment alone (low certainty).

1 finding from 1 review

Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis 2023 · Cochrane Headline outcomes only
RR 5.43 [1.21, 24.4]
4 studies · 989 participants
Low

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Dependency · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment showed no clear difference in dependency compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis 2023 · Cochrane Headline outcomes only
RR 1.51 [0.93, 2.45]
4 studies · 947 participants
Moderate

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Restenosis (≥ 50%) · people with symptomatic intracranial artery stenosis

The review found no eligible studies for this question.

1 finding from 1 review

Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Health‐related quality of life · people with symptomatic intracranial artery stenosis

The review found no eligible studies for this question.

1 finding from 1 review

Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Medical treatment vs placebo

Breast pain · women with breast engorgement

1 finding from 1 review

Treatments for breast engorgement during lactation 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 70 participants
Low

Medical treatment vs placebo

Breast induration/hardness · women with breast engorgement

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for breast engorgement during lactation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Medical treatment vs placebo

Breast swelling · women with breast engorgement

1 finding from 1 review

Treatments for breast engorgement during lactation 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 129 participants
Low

Medical treatment vs placebo

Breast engorgement · women with breast engorgement

1 finding from 1 review

Treatments for breast engorgement during lactation 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 115 participants
Low

Medical treatment vs placebo

Cessation of breastfeeding, · women with breast engorgement

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for breast engorgement during lactation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Medical treatment vs placebo

Number of women with adverse events, · women with breast engorgement

1 finding from 1 review

Treatments for breast engorgement during lactation 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 129 participants
Low

Endovascular therapy plus conventional medical treatment vs medical treatment

Death or stroke · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in 30‐day post‐randomisation death/stroke compared with medical treatment alone (low certainty).

1 finding from 1 review

Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis 2022 · Cochrane Headline outcomes only
RR 2.33 [0.77, 7.07]
3 studies · 349 participants
Low

Endovascular therapy plus conventional medical treatment vs medical treatment

Fatal/non‐fatal stroke in the territory of the treated vertebral artery stenosis(assessed after 30 days post‐randomisation to completion of · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in fatal/non‐fatal stroke in the territory of the treated vertebral… compared with medical treatment alone (moderate certainty).

1 finding from 1 review

Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis 2022 · Cochrane Headline outcomes only
RR 0.51 [0.26, 1.01]
3 studies · 349 participants
Moderate

Endovascular therapy plus conventional medical treatment vs medical treatment

Stroke (ischaemic or haemorrhagic)Median · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in stroke (ischaemic or haemorrhagic)Median compared with medical treatment alone (moderate certainty).

1 finding from 1 review

Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis 2022 · Cochrane Headline outcomes only
RR 0.77 [0.44, 1.32]
3 studies · 349 participants
Moderate

Endovascular therapy plus conventional medical treatment vs medical treatment

DeathMedian · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in deathMedian compared with medical treatment alone (low certainty).

1 finding from 1 review

Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis 2022 · Cochrane Headline outcomes only
RR 0.78 [0.37, 1.62]
3 studies · 349 participants
Low

Endovascular therapy plus conventional medical treatment vs medical treatment

Stroke or TIAMedian · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in stroke or TIAMedian compared with medical treatment alone (moderate certainty).

1 finding from 1 review

Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis 2022 · Cochrane Headline outcomes only
RR 0.65 [0.39, 1.06]
2 studies · 234 participants
Moderate