Findings

What do systematic reviews say?

15 questions · 15 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 4 · 26.7%Very low 5 · 33.3%Low 6 · 40%Moderate 0 · 0%High 0 · 0%

MS‐LE vs S‐LE

Mortality before hospital discharge · Parenterally fed preterm infants

1 finding from 1 review

Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
GRADE not reported

MS‐LE vs S‐LE

Days to regain birth weight · Parenterally fed preterm infants

1 finding from 1 review

Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

MS‐LE vs S‐LE

Rate of weight gain (g/kg/day) · Parenterally fed preterm infants

1 finding from 1 review

Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

MS‐LE vs S‐LE

Bronchopulmonary dysplasia/chronic lung disease · Parenterally fed preterm infants

It is very uncertain whether MS‐LE changes bronchopulmonary dysplasia/chronic lung disease compared with S‐LE (very low certainty).

1 finding from 1 review

Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
RR 1 [0.28, 3.63]
1 study · 60 participants
Very low

MS‐LE vs S‐LE

Any sepsis (clinical and/or culture positive) · Parenterally fed preterm infants

It is very uncertain whether MS‐LE changes any sepsis (clinical and/or culture positive) compared with S‐LE (very low certainty).

1 finding from 1 review

Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
RR 2 [0.67, 5.94]
1 study · 60 participants
Very low

MS‐LE vs S‐LE

Parenteral nutrition‐associated liver disease/cholestasis · Parenterally fed preterm infants

It is very uncertain whether MS‐LE changes parenteral nutrition‐associated liver disease/cholestasis compared with S‐LE (very low certainty).

1 finding from 1 review

Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
RR 3 [0.13, 70.83]
1 study · 60 participants
Very low

MS‐LE vs S‐LE

Hypertriglyceridaemia · Parenterally fed preterm infants

1 finding from 1 review

Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
GRADE not reported

Alternative lipid emulsion (LE) vs S‐LE

Growth rate – MS‐LE vs S‐LE · Parenterally fed preterm infants

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Alternative lipid emulsion (LE) vs S‐LE

Death of baby (up to discharge) · Parenterally fed preterm infants

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
GRADE not reported

Alternative lipid emulsion (LE) vs another alternative‐LE

Growth · Parenterally fed preterm infants

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Low

Alternative lipid emulsion (LE) vs another alternative‐LE

PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – MS‐LE vs OS‐LE · Parenterally fed preterm infants

Alternative lipid emulsion (LE) showed no clear difference in PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – MS‐LE vs OS‐LE compared with another alternative‐LE (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 2.9 [0.12, 68.5]
1 study · 59 participants
Low

Alternative lipid emulsion (LE) vs another alternative‐LE

Death at hospital discharge · Parenterally fed preterm infants

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
GRADE not reported

Alternative lipid emulsion (LE) vs another alternative‐LE

Oxygen requirement at 36 weeks' postmenstrual age · Parenterally fed preterm infants

Alternative lipid emulsion (LE) showed no clear difference in CLD (oxygen requirement at 36 weeks' postmenstrual age) – MS‐LE vs… compared with another alternative‐LE (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 0.77 [0.23, 2.6]
1 study · 59 participants
Low

Alternative lipid emulsion (LE) vs another alternative‐LE

Any sepsis (clinical and/or culture positive) · Parenterally fed preterm infants

Alternative lipid emulsion (LE) showed no clear difference in any sepsis (clinical or culture positive (or both)) – MS‐LE vs OS‐LE compared with another alternative‐LE (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 1.93 [0.65, 5.73]
1 study · 59 participants
Low

Alternative lipid emulsion (LE) vs another alternative‐LE

Conjugated bilirubin levels · Parenterally fed preterm infants

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Low