Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

259 questions · 260 findings · 27 reviews · Airways

No studies found 22 · 8.5%GRADE not reported 15 · 5.8%Very low 30 · 11.5%Low 99 · 38.1%Moderate 79 · 30.4%High 15 · 5.8%

Titrated oxygen therapy vs high‐flow oxygen therapy

Mortality (respiratory‐ related and all‐cause · adults with acute exacerbations of chronic obstructive pulmonary disease

Titrated oxygen therapy may leads to lower mortality (respiratory‐ related and all‐cause compared with high‐flow oxygen therapy (low certainty).

1 finding from 1 review

Titrated oxygen therapy vs high‐flow oxygen therapy

Ventilation of any type · adults with acute exacerbations of chronic obstructive pulmonary disease

Titrated oxygen therapy showed no clear difference in ventilation of any type compared with high‐flow oxygen therapy (low certainty).

1 finding from 1 review