What do systematic reviews say?

MFS‐LE vs S‐LE

• Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 57 participants
  Low

MFS‐LE vs S‐LE

MFS‐LE showed no clear difference in bronchopulmonary dysplasia/chronic lung disease compared with S‐LE (low certainty).

• Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
  RR 1.39 [0.42, 4.65]
  1 study · 57 participants
  Low

MFS‐LE vs S‐LE

MFS‐LE showed no clear difference in any sepsis (clinical and/or culture positive) compared with S‐LE (low certainty).

• Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
  RR 1.11 [0.31, 4.02]
  1 study · 57 participants
  Low

MFS‐LE vs S‐LE

MFS‐LE showed no clear difference in parenteral nutrition‐associated liver disease/cholestasis compared with S‐LE (low certainty).

• Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
  RR 3.32 [0.14, 78.25]
  1 study · 57 participants
  Low

MFS‐LE vs S‐LE

MFS‐LE showed no clear difference in death before discharge compared with S‐LE (low certainty).

• Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
  RR 5 [0.25, 99.95]
  1 study · 60 participants
  Low

MFS‐LE vs S‐LE

• Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 57 participants
  Low

Fish oil lipid emulsion (LE) vs another fish oil LE

• Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 55 participants
  Low

Fish oil lipid emulsion (LE) vs another fish oil LE

Fish oil lipid emulsion (LE) showed no clear difference in PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – MOFS‐LE vs MFS‐LE compared with another fish oil LE (low certainty).

• Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
  RR 0.96 [0.06, 14.65]
  1 study · 55 participants
  Low

Fish oil lipid emulsion (LE) vs another fish oil LE

Fish oil lipid emulsion (LE) showed no clear difference in death before discharge – MOFS‐LE vs MFS‐LE compared with another fish oil LE (low certainty).

• Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
  RR 1 [0.15, 6.64]
  1 study · 60 participants
  Low

Fish oil lipid emulsion (LE) vs another fish oil LE

Fish oil lipid emulsion (LE) showed no clear difference in CLD (oxygen requirement at 36 weeks' postmenstrual age) – MOFS‐LE vs… compared with another fish oil LE (low certainty).

• Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
  RR 1.16 [0.4, 3.35]
  1 study · 55 participants
  Low

Fish oil lipid emulsion (LE) vs another fish oil LE

Fish oil lipid emulsion (LE) showed no clear difference in any sepsis (clinical or culture positive (or both)) – MOFS‐LE vs… compared with another fish oil LE (low certainty).

• Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
  RR 1.69 [0.56, 5.11]
  1 study · 55 participants
  Low

Fish oil lipid emulsion (LE) vs another fish oil LE

• Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 55 participants
  Low