Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

373 questions · 383 findings · 25 reviews · Hepato-Biliary

No studies found 62 · 16.2%GRADE not reported 3 · 0.8%Very low 259 · 67.6%Low 51 · 13.3%Moderate 7 · 1.8%High 1 · 0.3%

Percutaneous ethanol injection vs no intervention, other ablation methods, or systemic treatment

Failure to clear liver metastases or recurrence of liver metastases · people with liver metastases

It is very uncertain whether percutaneous ethanol injection changes failure to clear liver metastases or recurrence of liver metastases compared with no intervention, other ablation methods, or systemic treatment (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Electrocoagulation in combination with allopurinol or with dimethyl sulphoxide vs control (vehicle solution of allopurinol by mouth)

All‐cause mortality at last · people with liver metastases

Summary of Findings Table ‐ Electrocoagulation in combination with… may leads to lower all‐cause mortality at last compared with control (vehicle solution of allopurinol by mouth) (low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Electrocoagulation in combination with allopurinol or with dimethyl sulphoxide vs control (vehicle solution of allopurinol by mouth)

Post‐operative deaths · people with liver metastases

It is very uncertain whether summary of Findings Table ‐ Electrocoagulation in combination with… changes post‐operative deaths compared with control (vehicle solution of allopurinol by mouth) (very low certainty).

1 finding from 1 review

Microwave coagulation vs radiofrequency ablation

Recurrence of liver metastases local progression · people with liver metastases

It is very uncertain whether microwave coagulation changes recurrence of liver metastases local progression compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Microwave coagulation vs radiofrequency ablation

Recurrence of liver metastases distant recurrence · people with liver metastases

It is very uncertain whether microwave coagulation changes recurrence of liver metastases distant recurrence compared with radiofrequency ablation (very low certainty).

1 finding from 1 review