Cochrane · systematic review · CD008717

Percutaneous ethanol injection for liver metastases

Swierz, MJ, Storman, D, Riemsma, RP, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
3
No studies
4
Included studies
NR
No studies 4 · 57.1%Ungraded 0 · 0%Very low 3 · 42.9%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Percutaneous ethanol injection compared to no intervention, other ablation methods, or systemic treatment for liver metastases

Population: patients with liver metastases
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality at last
Percutaneous ethanol injection vs no intervention, other ablation methods, or systemic treatment
RR 0.69 [0.36, 1.33]1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Time to mortality
Percutaneous ethanol injection vs no intervention, other ablation methods, or systemic treatment
no estimate extractedNRNo studies
Health‐related quality of life
Percutaneous ethanol injection vs no intervention, other ablation methods, or systemic treatment
no estimate extractedNRNo studies
Failure to clear liver metastases or recurrence of liver metastases
Percutaneous ethanol injection vs no intervention, other ablation methods, or systemic treatment
RR 0.41 [0.15, 1.15]1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Time to progression of liver metastases
Percutaneous ethanol injection vs no intervention, other ablation methods, or systemic treatment
no estimate extractedNRNo studies
Tumour response measures
Percutaneous ethanol injection vs no intervention, other ablation methods, or systemic treatment
no estimate extracted1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Serious adverse events and complications
Percutaneous ethanol injection vs no intervention, other ablation methods, or systemic treatment
no estimate extractedNRNo studies