Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

259 questions · 277 findings · 17 reviews · Skin · Headline outcomes only

No studies found 59 · 21.3%GRADE not reported 14 · 5.1%Very low 45 · 16.2%Low 58 · 20.9%Moderate 64 · 23.1%High 37 · 13.4%

Summary of findings table ‐ Oral classical immunosuppressants (betamethasone) vs oral classical immunosuppressants (azathioprine, methotrexate, prednisolone)

Short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of · adults with alopecia areata

Summary of findings table ‐ Oral classical immunosuppressants… showed no clear difference in short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of compared with oral classical immunosuppressants (azathioprine, methotrexate,… (low certainty).

1 finding from 1 review

Corticosteroid creams/ointments: mometasone furoate cream 3 times/week vs 2 times/week

Secondary: investigator‐rated reduction in severity ‐ Not measured · people (all patch‐tested) with hand eczema > 6 months that had cleared upon daily treatment for a maximum of 9 weeks with mometasone…

The review found no eligible studies for this question.

1 finding from 1 review

Corticosteroid creams/ointments: mometasone furoate cream 3 times/week vs 2 times/week

Primary: investigator‐rated good/excellent control of symptoms · people (all patch‐tested) with hand eczema > 6 months that had cleared upon daily treatment for a maximum of 9 weeks with mometasone…

Corticosteroid creams/ointments: mometasone furoate cream 3 times/week showed no clear difference in primary: investigator‐rated good/excellent control of symptoms compared with 2 times/week (low certainty).

1 finding from 1 review

Corticosteroid creams/ointments: mometasone furoate cream 3 times/week vs 2 times/week

Primary: participant‐rated good/excellent control of symptoms Not measured · people (all patch‐tested) with hand eczema > 6 months that had cleared upon daily treatment for a maximum of 9 weeks with mometasone…

The review found no eligible studies for this question.

1 finding from 1 review