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Evidence found and GRADE certainty

266 questions · 269 findings · 41 reviews · Eyes and Vision

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No studies found 85 · 31.6%GRADE not reported 3 · 1.1%Very low 62 · 23%Low 70 · 26%Moderate 46 · 17.1%High 3 · 1.1%

Low‐ vs high‐energy diode trans‐scleral cyclophotocoagulation

Control of intraocular pressure · people with primary open‐angle glaucoma and no previous glaucoma surgery

Low‐ showed no clear difference in control of intraocular pressure compared with high‐energy diode trans‐scleral cyclophotocoagulation (low certainty).

1 finding from 1 review

Low‐ vs high‐energy diode trans‐scleral cyclophotocoagulation

Proportion needing additional glaucoma surgery at 1‐year · people with primary open‐angle glaucoma and no previous glaucoma surgery

Low‐ showed no clear difference in additional glaucoma surgery compared with high‐energy diode trans‐scleral cyclophotocoagulation (low certainty).

1 finding from 1 review

LipiFlow vs basic warm compresses

Mean change from baseline in meibomian gland expression scores at 1 to 4 weeks (higher is favored) · people with dry eye

It is very uncertain whether lipiFlow changes mean change from baseline in meibomian gland expression scores at 1… compared with basic warm compresses (very low certainty).

1 finding from 1 review

LipiFlow vs basic warm compresses

Mean change from baseline in meibum quality scores at 1 to 4 weeks (higher is favored) · people with dry eye

It is very uncertain whether lipiFlow changes mean change from baseline in meibum quality scores at 1 to 4 weeks… compared with basic warm compresses (very low certainty).

1 finding from 1 review

LipiFlow vs thermostatic devices

Mean change from baseline in meibomian gland expression scores at 1 to 4 weeks (higher is favored) · people with dry eye

LipiFlow showed no clear difference in mean change from baseline in meibomian gland expression scores at 1… compared with thermostatic devices (low certainty).

1 finding from 1 review

LipiFlow vs thermostatic devices

Mean change from baseline in meibum quality scores at 1 to 4 weeks (higher is favored) · people with dry eye

LipiFlow showed no clear difference in mean change from baseline in meibum quality scores at 1 to 4 weeks… compared with thermostatic devices (low certainty).

1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants requiring further IOP‐lowering interventions (additional surgery, medications, or both) (lower number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

It is very uncertain whether phacoemulsification changes proportion of participants requiring further IOP‐lowering… compared with laser peripheral iridotomy (very low certainty).

1 finding from 1 review