Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,760 questions · 8,065 findings · 1,036 reviews

No studies found 1,686 · 20.9%GRADE not reported 675 · 8.4%Very low 1,953 · 24.2%Low 2,048 · 25.4%Moderate 1,296 · 16.1%High 407 · 5%

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Slow vs faster rates of enteral feed advancement

Necrotising enterocolitis · very preterm or very low birth weight infants

Slow showed no clear difference in necrotising enterocolitis before hospital discharge compared with faster rates of enteral feed advancement (moderate certainty).

1 finding from 1 review

Slow vs faster rates of enteral feed advancement

Mortality before hospital discharge · very preterm or very low birth weight infants

Slow showed no clear difference in mortality before hospital discharge compared with faster rates of enteral feed advancement (moderate certainty).

1 finding from 1 review

Slow vs faster rates of enteral feed advancement

Invasive infection (before hospital discharge) · very preterm or very low birth weight infants

Slow showed no clear difference in invasive infection before hospital discharge compared with faster rates of enteral feed advancement (low certainty).

1 finding from 1 review

Upper clear plastic retainer + lower fixed canine-to-canine retainer vs Upper clear plastic retainer + lower interproximal reduction (adjunctive), no lower retainer

Stability: Little's Irregularity Index (lower arch) · People who had received fixed appliance orthodontic treatment

Upper clear plastic retainer + lower fixed canine-to-canine retainer showed no clear difference in stability: Little's Irregularity Index (lower arch) compared with upper clear plastic retainer + lower interproximal reduction…; GRADE not reported.

1 finding from 1 review

ICU follow‐up services vs standard care or no follow‐up service

All‐cause mortality Time point of measurement: 2 months in 1 randomised study; 12 months in 3 randomised studies; 14 months in 1 non‐randomised study · adult survivors of the ICU, excluding those already in an existing follow‐up or rehabilitation programme
1 finding from 1 review