Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

96 questions · 104 findings · 15 reviews · ENT

No studies found 44 · 42.3%GRADE not reported 0 · 0%Very low 30 · 28.8%Low 19 · 18.3%Moderate 9 · 8.7%High 2 · 1.9%

Low‐dose adjuvant radiotherapy vs standard‐dose adjuvant radiotherapy

Voice (Voice Handicap Index) · patients with HPV‐positive oropharyngeal carcinoma who have received minimally invasive transoral surgery

The review found no eligible studies for this question.

1 finding from 1 review

Therapeutic swallowing exercises vs treatment

Swallowing function/efficiency Measured using a rating of oropharyngeal swallowing efficiency (OPSE) quantifying the interaction of the speed of bolus movement and safety/efficiency in clearing material from the oropharynx Dysphagia is defined as ... · adults with advanced head and neck cancer

It is very uncertain whether therapeutic swallowing exercises changes swallowing function/efficiency Measured using a rating of… compared with treatment (very low certainty).

1 finding from 1 review

Therapeutic swallowing exercises vs treatment

Adverse event: Weight loss (> 10%) Change in nutritional status reflected by a patient's weight at 6 weeks after treatment · adults with advanced head and neck cancer

It is very uncertain whether therapeutic swallowing exercises changes adverse event: Weight loss (> 10%) Change in nutritional status… compared with treatment (very low certainty).

2 findings from 1 review

Therapeutic swallowing exercises vs treatment

Adverse event: Weight change Patient's body weight 6 months before the start of treatment was retrieved from the patient's medical notes and "relative weight change" was calculated as the percentage weight change relative to the weight at week 0 6... · adults with advanced head and neck cancer

It is very uncertain whether therapeutic swallowing exercises changes adverse event: Weight change Patient's body weight 6 months before… compared with treatment (very low certainty).

1 finding from 1 review

Therapeutic swallowing exercises vs sham

Adverse event: Weight loss (> 10%) Change in nutritional status reflected by a patient's weight at 6 weeks after treatment · adults with advanced head and neck cancer

It is very uncertain whether therapeutic swallowing exercises changes adverse event: Weight loss (> 10%) Change in nutritional status… compared with sham intervention (very low certainty).

1 finding from 1 review

Intratympanic corticosteroids vs systemic corticosteroids

Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in change in hearing threshold determined by PTA Range 0 dB to 140 dB… compared with systemic corticosteroids (low certainty).

1 finding from 1 review

Intratympanic plus systemic corticosteroids (combined therapy) vs systemic corticosteroids alone

Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss

Intratympanic plus systemic corticosteroids (combined therapy) showed no clear difference in change in hearing threshold determined by PTA Range 0 dB to 140 dB… compared with systemic corticosteroids alone (low certainty).

1 finding from 1 review

Intratympanic plus systemic corticosteroids (combined therapy) vs systemic corticosteroids alone

Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss

It is very uncertain whether intratympanic plus systemic corticosteroids (combined therapy) changes final hearing threshold determined by PTA A lower value represents… compared with systemic corticosteroids alone (very low certainty).

1 finding from 1 review

Intratympanic corticosteroids vs no treatment or versus placebo

Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in change in hearing threshold determined by PTA Range 0 dB to 140 dB… compared with no treatment or versus placebo (low certainty).

1 finding from 1 review

Intratympanic corticosteroids vs no treatment or versus placebo

Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in final hearing threshold determined by PTA (a lower value represents… compared with no treatment or versus placebo (low certainty).

1 finding from 1 review

Intratympanic corticosteroids vs systemic corticosteroids

Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in final hearing threshold determined by PTA (a lower value represents… compared with systemic corticosteroids (low certainty).

1 finding from 1 review