Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

119 questions · 122 findings · 18 reviews · Common Mental Disorders

No studies found 29 · 23.8%GRADE not reported 12 · 9.8%Very low 39 · 32%Low 28 · 23%Moderate 14 · 11.5%High 0 · 0%

Brexpiprazole vs antidepressive agents

Adverse effects: 2. Extrapyramidal ‐ akathisia · participants of any age with a primary diagnosis of major depressive disorder

Brexpiprazole probably leads to higher adverse effects: akathisia (followed up until the end of the longest compared with antidepressive agents (moderate certainty).

1 finding from 1 review

Brexpiprazole vs antidepressive agents

Weight gain · participants of any age with a primary diagnosis of major depressive disorder

Brexpiprazole probably leads to higher adverse effects: weight gain (followed up until the end of the longest compared with antidepressive agents (moderate certainty).

1 finding from 1 review

Lamotrigine vs lithium

Withdrawal from treatment due to any reason, 6‐12 months after intervention initiation (long term) · bipolar disorder

Lamotrigine showed no clear difference in withdrawal from treatment due to any reason, 6‐12 months after… compared with lithium (moderate certainty).

1 finding from 1 review

Lamotrigine vs lithium

Any reported adverse effects 6‐12 months after initiating the intervention (long term) · bipolar disorder

Lamotrigine probably leads to lower any reported adverse effects 6‐12 months after initiating the… compared with lithium (moderate certainty).

1 finding from 1 review

Lamotrigine vs placebo

Withdrawal from treatment due to any reason, 6‐12 months after intervention initiation (long term) · bipolar disorder

Lamotrigine probably leads to lower withdrawal from treatment due to any reason, 6‐12 months after… compared with placebo (moderate certainty).

1 finding from 1 review

Lamotrigine vs placebo

Any reported adverse effects 6‐12 months after initiating the intervention (long term) · bipolar disorder

Lamotrigine showed no clear difference in any reported adverse effects 6‐12 months after initiating the… compared with placebo (moderate certainty).

1 finding from 1 review