Findings

What do systematic reviews say?

56 questions · 65 findings · 6 reviews

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No studies found 35 · 53.8%GRADE not reported 12 · 18.5%Very low 6 · 9.2%Low 7 · 10.8%Moderate 5 · 7.7%High 0 · 0%

Summary of findings: corticosteroid and local anaesthetic injection (CS+LA) vs local anaesthetic injection (LA)

Reduction in pain intensity · Morton's neuroma

1 finding from 1 review

Treatments for Morton's neuroma 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 157 participants
Low

Summary of findings: corticosteroid and local anaesthetic injection (CS+LA) vs local anaesthetic injection (LA)

Function: · Morton's neuroma

1 finding from 1 review

Treatments for Morton's neuroma 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 157 participants
Low

Summary of findings: corticosteroid and local anaesthetic injection (CS+LA) vs local anaesthetic injection (LA)

HRQoL: EQ‐5D (0 to 1; a higher score indicates improved HRQoL) (final values) · Morton's neuroma

1 finding from 1 review

Treatments for Morton's neuroma 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 122 participants
Moderate

Summary of findings: corticosteroid and local anaesthetic injection (CS+LA) vs local anaesthetic injection (LA)

Satisfaction: 4‐item Likert scale (dichotomised into satisfied and dissatisfied) · Morton's neuroma

Summary of findings: corticosteroid and local anaesthetic injection… showed no clear difference in satisfaction: Modified Johnson Scale (dichotomised into satisfied… compared with local anaesthetic injection (LA) (low certainty).

1 finding from 1 review

Treatments for Morton's neuroma 2024 · Cochrane Headline outcomes only
RR 1.08 [0.63, 1.85]
1 study · 35 participants
Low

Summary of findings: corticosteroid and local anaesthetic injection (CS+LA) vs local anaesthetic injection (LA)

Adverse events · Morton's neuroma

It is very uncertain whether summary of findings: corticosteroid and local anaesthetic injection… changes adverse events compared with local anaesthetic injection (LA) (very low certainty).

1 finding from 1 review

Treatments for Morton's neuroma 2024 · Cochrane Headline outcomes only
RR 9.84 [1.28, 75.56]
2 studies · 157 participants
Very low

Local anaesthetic injection vs no treatment/placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · septal surgery

The review found no eligible studies for this question.

3 findings from 1 review

Perioperative local anaesthesia for reducing pain following septal surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Perioperative local anaesthesia for reducing pain following septal surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Perioperative local anaesthesia for reducing pain following septal surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Local anaesthetic injection vs no treatment/placebo

Additional analgesia required (escape analgesia) · septal surgery

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative local anaesthesia for reducing pain following septal surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Local anaesthetic injection vs no treatment/placebo

Duration of hospitalisation ‐ not reported · septal surgery

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative local anaesthesia for reducing pain following septal surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Local anaesthetic injection vs no treatment/placebo

Vomiting ‐ postoperative · septal surgery

Local anaesthetic injection showed no clear difference in adverse effect (postoperative vomiting) compared with no treatment/placebo (low certainty).

1 finding from 1 review

Perioperative local anaesthesia for reducing pain following septal surgery 2018 · Cochrane Headline outcomes only
OR 3.1 [0.12, 79.23]
1 study · 60 participants
Low

Local anaesthetic injection vs no treatment/placebo

Adverse effect (postoperative bleeding) ‐ not reported · septal surgery

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative local anaesthesia for reducing pain following septal surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs injection with corticosteroid and anaesthetic

Adverse events · Morton's neuroma

Summary of findings: ultrasound‐guided injection of corticosteroid… showed no clear difference in adverse events compared with non‐ultrasound‐guided injection of corticosteroid and local… (low certainty).

1 finding from 1 review

Treatments for Morton's neuroma 2024 · Cochrane Headline outcomes only
RR 0.42 [0.12, 1.39]
2 studies · 116 participants
Low

Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs injection with corticosteroid and anaesthetic

Pain at short term (4 weeks) VAS 10‐cm scale, which was translated to a 0 to 100 scale in which lower scores mean less pain. · Morton's neuroma

1 finding from 1 review

Treatments for Morton's neuroma 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 116 participants
Moderate

Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs injection with corticosteroid and anaesthetic

Function: · Morton's neuroma

1 finding from 1 review

Treatments for Morton's neuroma 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 116 participants
Moderate

Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs injection with corticosteroid and anaesthetic

Health‐related quality of life · Morton's neuroma

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for Morton's neuroma 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs injection with corticosteroid and anaesthetic

Satisfaction: 4‐item Likert scale (dichotomised into satisfied and dissatisfied) · Morton's neuroma

Summary of findings: ultrasound‐guided injection of corticosteroid… may leads to higher satisfaction: 4‐point Likert scale (dichotomised into satisfied and… compared with non‐ultrasound‐guided injection of corticosteroid and local… (low certainty).

1 finding from 1 review

Treatments for Morton's neuroma 2024 · Cochrane Headline outcomes only
RR 1.71 [1.19, 2.44]
2 studies · 114 participants
Low

Infiltration injection local anaesthetic vs no treatment or placebo

Lip or cheek biting · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
Coulthard 2006: lip/cheek biting 3/70 (LA) vs 1/69 (placebo), P=0.62; Townsend 2009: 4/11 vs 1/12, P=0.16; no statistically significant difference
2 studies · 162 participants
GRADE not reported

Infiltration injection local anaesthetic vs no treatment or placebo

Parental satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
No study reported parental satisfaction
0 studies
No studies found

Infiltration injection local anaesthetic vs no treatment or placebo

Participant satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
None of the studies reported on patient or child satisfaction
0 studies
No studies found

Infiltration injection local anaesthetic vs no treatment or placebo

Intraoperative or postoperative bleeding · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
Because of substantial clinical and methodological heterogeneity in the studies, we were unable to determine an estimate of effect
2 studies · 174 participants
Very low

Infiltration injection local anaesthetic vs no treatment or placebo

Postoperative pain or distress · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
Postoperatively, typically up to discharge
Because of substantial clinical and methodological heterogeneity in the studies, we were unable to determine an estimate of effect
6 studies · 542 participants
Very low