Findings

What do systematic reviews say?

32 questions · 32 findings · 3 reviews · Hepato-Biliary · Headline outcomes only

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No studies found 2 · 6.3%GRADE not reported 0 · 0%Very low 26 · 81.3%Low 3 · 9.4%Moderate 1 · 3.1%High 0 · 0%

Infiltration injection local anaesthetic vs no local anaesthetic wound infiltration

All‐cause mortality · patients with people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 539 participants
Very low

Infiltration injection local anaesthetic vs no local anaesthetic wound infiltration

Serious adverse events · patients with people undergoing laparoscopic cholecystectomy.

It is very uncertain whether local anaesthetic wound infiltration changes serious adverse events compared with no local anaesthetic wound infiltration (very low certainty).

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
RR 2 [0.19, 21.59]
7 studies · 539 participants
Very low

Infiltration injection local anaesthetic vs no local anaesthetic wound infiltration

Proportion discharged as day surgery · patients with people undergoing laparoscopic cholecystectomy.

It is very uncertain whether local anaesthetic wound infiltration changes proportion discharged as day surgery compared with no local anaesthetic wound infiltration (very low certainty).

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
RR 1.55 [1.05, 2.28]
1 study · 97 participants
Very low

Infiltration injection local anaesthetic vs no local anaesthetic wound infiltration

Length of hospital stay · patients with people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 327 participants
Very low

Infiltration injection local anaesthetic vs no local anaesthetic wound infiltration

Pain 4 to 8 hours · patients with people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 806 participants
Very low

Infiltration injection local anaesthetic vs no local anaesthetic wound infiltration

Pain 9 to 24 hours · patients with people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 756 participants
Low

Infiltration injection local anaesthetic vs no local anaesthetic wound infiltration

Return to normal activity · patients with people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 195 participants
Very low

Local anaesthetic wound infiltration before incision vs end of surgery

All‐cause mortality · patients with people undergoing laparoscopic cholecystectomy

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Very low

Local anaesthetic wound infiltration before incision vs end of surgery

Serious adverse events · patients with people undergoing laparoscopic cholecystectomy

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Very low

Local anaesthetic wound infiltration before incision vs end of surgery

Pain 4 to 8 hours · patients with people undergoing laparoscopic cholecystectomy

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 76 participants
Very low

Local anaesthetic wound infiltration before incision vs end of surgery

Pain 9 to 24 hours · patients with people undergoing laparoscopic cholecystectomy

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Local anaesthetic wound infiltration before incision vs end of surgery

Return to normal activity · patients with people undergoing laparoscopic cholecystectomy

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

All‐cause mortality · people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 446 participants
Very low

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

Serious adverse events · people undergoing laparoscopic cholecystectomy.

It is very uncertain whether summary of findings table ‐ Intraperitoneal local anaesthetic changes serious adverse events compared with control (very low certainty).

1 finding from 1 review

Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
RR 1.07 [0.49, 2.34]
13 studies · 988 participants
Very low

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

Health related quality of life ‐ not measured · people undergoing laparoscopic cholecystectomy.

The review found no eligible studies for this question.

1 finding from 1 review

Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

Length of hospital stay · people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 936 participants
Moderate

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

Proportion discharged as day surgery · people undergoing laparoscopic cholecystectomy.

It is very uncertain whether summary of findings table ‐ Intraperitoneal local anaesthetic changes proportion discharged as day surgery compared with control (very low certainty).

1 finding from 1 review

Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
RR 1.43 [0.64, 3.2]
3 studies · 242 participants
Very low

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

Pain (4 to 8 hours)Scale from: 1 to 10 · people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
no estimate extracted
57 studies · 4046 participants
Low

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

Pain (9 to 24 hours)Scale from: 1 to 10 · people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
no estimate extracted
52 studies · 3588 participants
Low

Intervention not reported

Length of hospital stay · people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 137 participants
Very low