Pain with aspiration – local anaesthetica,b,d,e · people requesting a surgical abortion at less than 11 weeks' gestation (Renner 2016) and seven to 12 weeks' gestation (Glantz 2001)
1 finding from 1 review
Pain during abdominal entry (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Intraperitoneal lidocaine instillation may leads to lower number of women requiring rescue medication compared with intramuscular morphine (low certainty).
1 finding from 1 review
RR 0.22 [0.09, 0.54]
Studies not reported
Low
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Combination of intraperitoneal lidocaine instillation and… may leads to lower number of women requiring rescue medication compared with placebo (low certainty).
1 finding from 1 review
RR 0.11 [0.03, 0.42]
Studies not reported
Low
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Combination of lidocaine intraperitoneal instillation plus… showed no clear difference in number of women requiring rescue medication compared with lidocaine intraperitoneal instillation alone (low certainty).
1 finding from 1 review
RR 0.5 [0.1, 2.43]
Studies not reported
Low
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Combination of lidocaine intraperitoneal instillation plus… may leads to lower number of women requiring rescue medication compared with intramuscular morphine alone (low certainty).
1 finding from 1 review
RR 0.11 [0.03, 0.42]
Studies not reported
Low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
EMLA cream may leads to lower number of women requiring rescue medication compared with placebo (low certainty).
1 finding from 1 review
RR 0.36 [0.25, 0.53]
Studies not reported
Low
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
It is very uncertain whether lidocaine instillation changes adverse events within 48 hours post operation compared with placebo (very low certainty).
1 finding from 1 review
RR 1.04 [0.4, 2.69]
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Lidocaine instillation may leads to lower number of women requiring rescue medication compared with placebo (low certainty).
1 finding from 1 review
RR 0.27 [0.17, 0.44]
Studies not reported
Low
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low