Local haemorrhage · patients with symptomatic or asymptomatic carotid disease
Local anaesthesia showed no clear difference in local haemorrhage compared with general anaesthesia (moderate certainty).
1 finding from 1 review
Any stroke within 30 days of operation (primary outcome) · patients with symptomatic or asymptomatic carotid disease
1 finding from 1 review
Death within 30 days of operation · patients with symptomatic or asymptomatic carotid disease
Local anaesthesia showed no clear difference in death within 30 days of operation compared with general anaesthesia (low certainty).
1 finding from 1 review
Perioperative ipsilateral stroke (< 30 days) · patients with symptomatic or asymptomatic carotid disease
Local anaesthesia showed no clear difference in ipsilateral stroke within 30 days of operation compared with general anaesthesia (low certainty).
1 finding from 1 review
Perioperative death and strokes · patients with symptomatic or asymptomatic carotid disease
Local anaesthesia showed no clear difference in stroke or death within 30 days of operation compared with general anaesthesia (moderate certainty).
1 finding from 1 review
Myocardial infarction (0 to 30 days) · patients with symptomatic or asymptomatic carotid disease
Local anaesthesia showed no clear difference in myocardial infarction within 30 days of operation compared with general anaesthesia (low certainty).
1 finding from 1 review
Arteries shunted · patients with symptomatic or asymptomatic carotid disease
Local anaesthesia may leads to lower arteries shunted compared with general anaesthesia (low certainty).
1 finding from 1 review
Proportion given local anaesthesia (%) · heavy menstrual bleeding
It is very uncertain whether overall analyses: second‐generation endometrial ablation changes proportion given local anaesthesia (%) compared with first‐generation endometrial ablation (very low certainty).
1 finding from 1 review
Adverse effects of epidural anaesthesia ‐ not reported · Patients undergoing thoracotomy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Adverse effects of local or regional anaesthesia ‐ not reported · women after caesarean section
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Persistent pain 3 to 12 months after breast cancer surgery (We defined persistent postsurgical pain as new pain that did not exist before the operation, measured using differences in scores based on validated pain scales; patient interview between... · women with breast cancer undergoing elective surgery
Regional anaesthesia may leads to lower persistent pain 3 to 12 months after breast cancer surgery (We… compared with conventional pain control (low certainty).
1 finding from 1 review
Adverse effects of paravertebral block for breast cancer surgery · women with breast cancer undergoing elective surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Persistent pain 3 to 18 months after thoracotomy (We defined persistent postsurgical pain as new pain that did not exist before the operation, measured using differences in scores based on validated pain scales; patient interview between 3 to 18 m... · Patients undergoing thoracotomy
Thoracic epidural anaesthesia probably leads to lower persistent pain 3 to 18 months after thoracotomy (We defined… compared with conventional pain control (moderate certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · septal surgery
The review found no eligible studies for this question.
3 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Additional analgesia required (escape analgesia) · septal surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Duration of hospitalisation ‐ not reported · septal surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Vomiting ‐ postoperative · septal surgery
Local anaesthetic injection showed no clear difference in adverse effect (postoperative vomiting) compared with no treatment/placebo (low certainty).
1 finding from 1 review
Adverse effect (postoperative bleeding) ‐ not reported · septal surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · septal surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Additional analgesia required (escape analgesia) · septal surgery
Local anaesthetic application via nasal packing probably leads to lower requirement for additional analgesia compared with no packing/packing with placebo (moderate certainty).
1 finding from 1 review