What do systematic reviews say?

Levofloxacin vs ciprofloxacin

It is very uncertain whether levofloxacin changes microbiological efficacy ‐ pathogen eradication compared with ciprofloxacin (very low certainty).

• Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
  RR 1.18 [0.81, 1.71]
  2 studies · 669 participants
  Very low

Levofloxacin vs fluoroquinolones

It is very uncertain whether levofloxacin changes microbiological efficacy ‐ pathogen eradication compared with comparator fluoroquinolone (very low certainty).

• Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
  RR 1.12 [0.84, 1.48]
  3 studies · 758 participants
  Very low

Levofloxacin vs fluoroquinolones

• Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported
• Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Levofloxacin vs fluoroquinolones

Levofloxacin showed no clear difference in adverse effects of treatment ‐ any adverse effects compared with comparator fluoroquinolone (moderate certainty).

• Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
  RR 0.88 [0.72, 1.08]
  3 studies · 874 participants
  Moderate

Levofloxacin vs ciprofloxacin

Levofloxacin showed no clear difference in clinical efficacy ‐ cure or improvement at end of treatment compared with ciprofloxacin (low certainty).

• Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
  RR 1.16 [0.93, 1.46]
  2 studies · 669 participants
  Low
• Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
  RR 1.16 [0.86, 1.55]
  2 studies · 669 participants
  Very low

Levofloxacin vs ciprofloxacin

Levofloxacin showed no clear difference in adverse effects of treatment ‐ any adverse effects compared with ciprofloxacin (moderate certainty).

• Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
  RR 0.86 [0.7, 1.06]
  2 studies · 785 participants
  Moderate