Cochrane · systematic review · CD009071
Antimicrobial therapy for chronic bacterial prostatitis
Perletti, G, Marras, E, Wagenlehner, FME, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
UrologyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
16
current version
GRADE rated
12
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 4 · 25%Very low 6 · 37.5%Low 2 · 12.5%Moderate 4 · 25%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Levofloxacin versus ciprofloxacin for chronic bacterial prostatitis
Population: patients with chronic bacterial prostatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Microbiological efficacy ‐ pathogen eradication Levofloxacin vs ciprofloxacin | RR 1.18 [0.81, 1.71] | 2 studies · 669 participants | Very low Downgraded: risk of bias, inconsistency |
Clinical efficacy ‐ cure or improvement at end of treatment Levofloxacin vs ciprofloxacin | RR 1.16 [0.93, 1.46] | 2 studies · 669 participants | Low Downgraded: risk of bias |
Clinical efficacy ‐ cure or improvement at Levofloxacin vs ciprofloxacin | RR 1.16 [0.86, 1.55] | 2 studies · 669 participants | Very low Downgraded: risk of bias, inconsistency |
Adverse effects of treatment ‐ any adverse effects Levofloxacin vs ciprofloxacin | RR 0.86 [0.7, 1.06] | 2 studies · 785 participants | Moderate Downgraded: risk of bias |
Lomefloxacin versus comparator fluoroquinolone for chronic bacterial prostatitis
Population: patients with chronic bacterial prostatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Microbiological efficacy ‐ pathogen eradication at Lomefloxacin vs comparator fluoroquinolone | RR 0.96 [0.8, 1.16] | 2 studies · 116 participants | Low Downgraded: risk of bias |
Clinical efficacy ‐ cure or improvement at end of treatment Lomefloxacin vs comparator fluoroquinolone | no estimate extracted | 0 studies · 0 participants | Ungraded |
Clinical efficacy ‐ cure or improvement at Lomefloxacin vs comparator fluoroquinolone | no estimate extracted | 0 studies · 0 participants | Ungraded |
Adverse effects of treatment ‐ any adverse effects Lomefloxacin vs comparator fluoroquinolone | RR 0.64 [0.34, 1.21] | 2 studies · 215 participants | Moderate Downgraded: risk of bias |
Ciprofloxacin versus comparator fluoroquinolone for chronic bacterial prostatitis
Population: patients with chronic bacterial prostatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Microbiological efficacy ‐ pathogen eradication at end of treatment Ciprofloxacin vs comparator fluoroquinolone | RR 0.91 [0.7, 1.18] | 3 studies · 851 participants | Very low Downgraded: risk of bias, inconsistency |
Clinical efficacy ‐ cure or improvement at end of treatment Ciprofloxacin vs comparator fluoroquinolone | RR 0.9 [0.75, 1.08] | 3 studies · 851 participants | Very low Downgraded: risk of bias, inconsistency |
Clinical efficacy ‐ cure or improvement at Ciprofloxacin vs comparator fluoroquinolone | RR 0.93 [0.72, 1.2] | 3 studies · 851 participants | Very low Downgraded: risk of bias, inconsistency |
Adverse effects of treatment ‐ any adverse effects Ciprofloxacin vs comparator fluoroquinolone | RR 1.16 [0.95, 1.42] | 3 studies · 967 participants | Moderate Downgraded: risk of bias |
Levofloxacin versus comparator fluoroquinolone for chronic bacterial prostatitis
Population: patients with chronic bacterial prostatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Microbiological efficacy ‐ pathogen eradication Levofloxacin vs comparator fluoroquinolone | RR 1.12 [0.84, 1.48] | 3 studies · 758 participants | Very low Downgraded: risk of bias, inconsistency |
Clinical efficacy ‐ cure or improvement at end of treatment Levofloxacin vs comparator fluoroquinolone | no estimate extracted | 0 studies · 0 participants | Ungraded |
Clinical efficacy ‐ cure or improvement at Levofloxacin vs comparator fluoroquinolone | no estimate extracted | 0 studies · 0 participants | Ungraded |
Adverse effects of treatment ‐ any adverse effects Levofloxacin vs comparator fluoroquinolone | RR 0.88 [0.72, 1.08] | 3 studies · 874 participants | Moderate Downgraded: risk of bias |