What do systematic reviews say?

Lateral pararectal vs transrectal enterostomy placement

It is very uncertain whether lateral pararectal changes parastomal hernia (NRS) clinical examination, CT scan, or botha compared with transrectal enterostomy placement (very low certainty).

• Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation 2019 · Cochrane Headline outcomes only
  RR 1.22 [0.84, 1.75]
  10 studies · 864 participants
  Very low

Lateral pararectal vs transrectal enterostomy placement

Lateral pararectal showed no clear difference in parastomal hernia (RCT) clinical exam, sonography, intraoperatively,… compared with transrectal enterostomy placement (low certainty).

• Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation 2019 · Cochrane Headline outcomes only
  RR 1.34 [0.4, 4.48]
  1 study · 56 participants
  Low

Lateral pararectal vs transrectal enterostomy placement

It is very uncertain whether lateral pararectal changes stomal prolapse clinical exam, documented on a standard pro forma compared with transrectal enterostomy placement (very low certainty).

• Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation 2019 · Cochrane Headline outcomes only
  RR 1.23 [0.39, 3.85]
  1 study · 145 participants
  Very low

Lateral pararectal vs transrectal enterostomy placement

Lateral pararectal showed no clear difference in ileus or stenosis clinical exam, sonography compared with transrectal enterostomy placement (low certainty).

• Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation 2019 · Cochrane Headline outcomes only
  RR 2 [0.19, 20.9]
  1 study · 60 participants
  Low

Lateral pararectal vs transrectal enterostomy placement

Lateral pararectal showed no clear difference in skin irritation clinical exam, intraoperative exam, or both, during… compared with transrectal enterostomy placement (moderate certainty).

• Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation 2019 · Cochrane Headline outcomes only
  RR 0.67 [0.21, 2.13]
  1 study · 60 participants
  Moderate

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  16 studies · 1346 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 28 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

It is very uncertain whether early enteral nutrition within 24 hours of lower gastrointestinal… changes wound infection compared with later commencement (very low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 0.99 [0.64, 1.52]
  12 studies · 1181 participants
  Very low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in intraabdominal abscess compared with later commencement (low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 1 [0.26, 3.8]
  6 studies · 554 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in anastomotic leakage/dehiscence compared with later commencement (low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 0.78 [0.38, 1.61]
  13 studies · 1232 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in pneumonia (within hospital stay) compared with later commencement (low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 0.88 [0.32, 2.42]
  10 studies · 954 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in mortality compared with later commencement (low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 0.56 [0.21, 1.52]
  12 studies · 1179 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in vomiting compared with later commencement (low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 1.23 [0.96, 1.58]
  7 studies · 613 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in nausea compared with later commencement (low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 0.95 [0.71, 1.26]
  2 studies · 118 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

It is very uncertain whether early enteral nutrition within 24 hours of lower gastrointestinal… changes nausea and vomiting compared with later commencement (very low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 0.92 [0.6, 1.41]
  4 studies · 238 participants
  Very low

Open vs closed partial lateral internal sphincterotomy

Open showed no clear difference in persistence of the anal fissure compared with closed partial lateral internal sphincterotomy (high certainty).

• Operative procedures for fissure in ano 2011 · Cochrane Headline outcomes only
  OR 1 [0.4, 2.48]
  5 studies · 336 participants
  High

Open vs closed partial lateral internal sphincterotomy

Open showed no clear difference in minor incontinence to flatus compared with closed partial lateral internal sphincterotomy (moderate certainty).

• Operative procedures for fissure in ano 2011 · Cochrane Headline outcomes only
  OR 0.87 [0.41, 1.83]
  5 studies · 336 participants
  Moderate

Intervention not reported

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 1156 participants
  Low

Intervention not reported

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 190 participants
  Low

Intervention not reported

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 1075 participants
  Low