Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

764 questions · 795 findings · 110 reviews

No studies found 202 · 25.4%GRADE not reported 100 · 12.6%Very low 225 · 28.3%Low 155 · 19.5%Moderate 85 · 10.7%High 28 · 3.5%

Later vs earlier initiation of dexamethasone therapy

Death or bronchopulmonary dysplasia at 36 weeks PMA · preterm infants at risk for bronchopulmonary dysplasia

Later showed no clear difference in death or bronchopulmonary dysplasia at 36 weeks' PMA compared with earlier initiation of dexamethasone therapy (low certainty).

1 finding from 1 review

Later vs earlier initiation of dexamethasone therapy

Death or cerebral palsy at 1 to 3 years · preterm infants at risk for bronchopulmonary dysplasia

Later showed no clear difference in death or cerebral palsy at 1 to 3 years compared with earlier initiation of dexamethasone therapy (low certainty).

1 finding from 1 review

Later vs earlier initiation of dexamethasone therapy

Death or abnormal neurodevelopmental outcome (various definitions) · preterm infants at risk for bronchopulmonary dysplasia

Later showed no clear difference in death or abnormal neurodevelopmental outcome (various definitions) compared with earlier initiation of dexamethasone therapy (low certainty).

1 finding from 1 review

Summary of findings: bilateral laminotomy vs conventional laminectomy

Disability Long‐term (≥ 12 months) Disability scores converted to 0 to 100 scale to allow for comparison of different disability scales (RMDQ, ODI, JOA) · patients with lumbar stenosis

It is very uncertain whether summary of findings: bilateral laminotomy changes standardized Disability Index (0 to 100) Bilateral laminotomy… compared with conventional laminectomy (very low certainty).

1 finding from 1 review

Summary of findings: bilateral laminotomy vs conventional laminectomy

Satisfactory recovery Bilateral laminotomy compared with conventional laminectomy Satisfactory recovery was defined as 'good' or 'excellent' self‐perceived recovery · patients with lumbar stenosis

Summary of findings: bilateral laminotomy may leads to higher satisfactory recovery Bilateral laminotomy compared with… compared with conventional laminectomy (low certainty).

1 finding from 1 review

Summary of findings: bilateral laminotomy vs conventional laminectomy

VAS leg (0 to 10) Bilateral laminotomy compared with conventional laminectomy · patients with lumbar stenosis

It is very uncertain whether summary of findings: bilateral laminotomy changes VAS leg (0 to 10) Bilateral laminotomy compared with conventional… compared with conventional laminectomy (very low certainty).

1 finding from 1 review

Summary of findings: bilateral laminotomy vs conventional laminectomy

VAS back (0 to 10) Unilateral laminotomy compared with conventional laminectomy · patients with lumbar stenosis

Summary of findings: bilateral laminotomy showed no clear difference in VAS back (0 to 10) Unilateral laminotomy compared with conventional… compared with conventional laminectomy (low certainty).

1 finding from 1 review

Summary of findings: unilateral laminotomy vs conventional laminectomy

VAS back (0 to 10) Unilateral laminotomy compared with conventional laminectomy · patients with lumbar stenosis

It is very uncertain whether summary of findings: unilateral laminotomy changes VAS back (0 to 10) Unilateral laminotomy compared with conventional… compared with conventional laminectomy (very low certainty).

1 finding from 1 review

Summary of findings: unilateral laminotomy vs conventional laminectomy

Disability Long‐term (≥ 12 months) Disability scores converted to 0 to 100 scale to allow for comparison of different disability scales (RMDQ, ODI, JOA) · patients with lumbar stenosis

Summary of findings: unilateral laminotomy showed no clear difference in standardised Disability Index (0 to 100) Unilateral laminotomy… compared with conventional laminectomy (low certainty).

1 finding from 1 review

Summary of findings: unilateral laminotomy vs conventional laminectomy

Satisfactory recovery Bilateral laminotomy compared with conventional laminectomy Satisfactory recovery was defined as 'good' or 'excellent' self‐perceived recovery · patients with lumbar stenosis

Summary of findings: unilateral laminotomy showed no clear difference in satisfactory recovery Unilateral laminotomy compared with… compared with conventional laminectomy (low certainty).

1 finding from 1 review

Summary of findings: unilateral laminotomy vs conventional laminectomy

VAS leg (0 to 10) Unilateral laminotomy compared with conventional laminectomy · patients with lumbar stenosis

Summary of findings: unilateral laminotomy showed no clear difference in VAS leg (0 to 10) Unilateral laminotomy compared with conventional… compared with conventional laminectomy (low certainty).

1 finding from 1 review