Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

29 questions · 29 findings · 4 reviews

No studies found 11 · 37.9%GRADE not reported 0 · 0%Very low 2 · 6.9%Low 9 · 31%Moderate 5 · 17.2%High 2 · 6.9%

Laser photocoagulation vs no intervention

Worsening of BCVA defined as ≥ 15 ETDRS letters (i.e. 3 ETDRS lines or 0.3 logMAR · people with diabetic macular oedema

Laser photocoagulation probably leads to lower worsening of BCVA defined as ≥ 15 ETDRS letters (i.e. 3 ETDRS lines… compared with no intervention (moderate certainty).

1 finding from 1 review

Laser photocoagulation vs no intervention

Anatomic measures: partial to complete resolution of the macular oedema with stereoscopic fundus photography or biomicroscopy; leakage on fluorescein angiography (IVFA); and, if available, retinal macular thickness with OCT · people with diabetic macular oedema

Laser photocoagulation probably leads to higher anatomic measures: partial to complete resolution of the macular… compared with no intervention (moderate certainty).

1 finding from 1 review

Systemic administration of beta‐blockers vs placebo or no treatment

Treatment with laser photocoagulation or cryotherapy · Prevention of retinopathy of prematurity in preterm infants

Systemic administration of beta‐blockers may leads to lower treatment with laser photocoagulation or cryotherapy compared with placebo or no treatment (low certainty).

1 finding from 1 review