Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

9 questions · 10 findings · 2 reviews · Skin

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 30%Low 6 · 60%Moderate 1 · 10%High 0 · 0%

Ketoconazole vs placebo

Failure to achieve complete resolution Clinical assessment · patients with seborrhoeic dermatitis

Ketoconazole may leads to lower failure to achieve complete resolution Clinical assessment compared with placebo (low certainty).

1 finding from 1 review

Ketoconazole vs placebo

Side effects Self report · patients with seborrhoeic dermatitis

It is very uncertain whether ketoconazole changes side effects Self report compared with placebo (very low certainty).

1 finding from 1 review

Ketoconazole vs steroids

Failure to achieve complete resolution (combined for face and scalp) Clinical assessment · patients with seborrhoeic dermatitis

Ketoconazole showed no clear difference in failure to achieve complete resolution (combined for face and scalp)… compared with steroids (low certainty).

1 finding from 1 review

Ketoconazole vs steroids

Side effects (combined for face and scalp) Self report · patients with seborrhoeic dermatitis

Ketoconazole probably leads to lower side effects (combined for face and scalp) Self report compared with steroids (moderate certainty).

1 finding from 1 review

Ketoconazole vs ciclopirox

Failure to achieve complete resolution ‐ Face only Clinical assessment · patients with seborrhoeic dermatitis

Ketoconazole showed no clear difference in failure to achieve complete resolution ‐ Face only Clinical assessment compared with ciclopirox (low certainty).

1 finding from 1 review

Ketoconazole vs ciclopirox

Failure to achieve complete resolution (long term) ‐ Face only Clinical assessment · patients with seborrhoeic dermatitis

Ketoconazole showed no clear difference in failure to achieve complete resolution (long term) ‐ Face only… compared with ciclopirox (low certainty).

1 finding from 1 review

Ketoconazole vs ciclopirox

Side effects ‐ Scalp only Self reported · patients with seborrhoeic dermatitis

It is very uncertain whether ketoconazole changes side effects ‐ Scalp only Self reported compared with ciclopirox (very low certainty).

1 finding from 1 review

Complete cure for ketoconazole vs griseofulvin

Proportion of participants with complete cure · children infected with Trichophyton

Complete cure for ketoconazole showed no clear difference in proportion of participants with complete cure compared with griseofulvin (low certainty).

2 findings from 1 review